RT Journal Article
ID 212585547e9a0a62
A1 Denisova, Nina P.
A1 Mikhailov, Vladimir N.
A1 Petrishchev, Nickolay N.
T1 Thrombolytic Activity of Mushroom Proteinases: Thrombolytic Activity of Proteinases from Coprinus domesticus, C. cinereus, and Cerrena unicolor
JF International Journal of Medicinal Mushrooms
JO IJM
YR 1999
FD 1999-04-28
VO 1
IS 2
SP 187
OP 190
K1 Higher Basidiomycetes
K1 extracellular proteinases
K1 thrombolytic effect
K1 Coprinus species
K1 Cerrena unicolor.
AB Fibrinolytic and thrombolytic activity of extracellular enzyme complexes from the cultures of coprotrophic mushrooms Coprinus domesticus (Bolt.: Fr.) S. F. Gray and С. Cinnereus (Schaeff.: Fr.) S. F. Gray, as well as xylotrophic mushroom, Cerrena unicolor (Bull.: Fr.) Murr., were investigated during biomedical experiments in vitro and in vivo. It was shown that enzyme complexes isolated from C. domesticus, C. cinereus, and Cerrena unicolor possess a large affinity for fibrin and cause fibrin lysis. In addition, a direct and stable thrombolytic effect developed, proving more significant in fresh thrombosis.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,467a6b9619790c8f,212585547e9a0a62.html