RT Journal Article ID 212585547e9a0a62 A1 Denisova, Nina P. A1 Mikhailov, Vladimir N. A1 Petrishchev, Nickolay N. T1 Thrombolytic Activity of Mushroom Proteinases: Thrombolytic Activity of Proteinases from Coprinus domesticus, C. cinereus, and Cerrena unicolor JF International Journal of Medicinal Mushrooms JO IJM YR 1999 FD 1999-04-28 VO 1 IS 2 SP 187 OP 190 K1 Higher Basidiomycetes K1 extracellular proteinases K1 thrombolytic effect K1 Coprinus species K1 Cerrena unicolor. AB Fibrinolytic and thrombolytic activity of extracellular enzyme complexes from the cultures of coprotrophic mushrooms Coprinus domesticus (Bolt.: Fr.) S. F. Gray and С. Cinnereus (Schaeff.: Fr.) S. F. Gray, as well as xylotrophic mushroom, Cerrena unicolor (Bull.: Fr.) Murr., were investigated during biomedical experiments in vitro and in vivo. It was shown that enzyme complexes isolated from C. domesticus, C. cinereus, and Cerrena unicolor possess a large affinity for fibrin and cause fibrin lysis. In addition, a direct and stable thrombolytic effect developed, proving more significant in fresh thrombosis. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,467a6b9619790c8f,212585547e9a0a62.html