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Critical Reviews™ in Physical and Rehabilitation Medicine
Ассоциированный редактор: Rajani Mullerpatan (open in a new tab)

Выходит 4 номеров в год

ISSN Печать: 0896-2960

ISSN Онлайн: 2162-6553

SJR: 0.141 SNIP: 0.129 CiteScore™:: 0.6 H-Index: 18

Indexed in

Fibromyalgia Syndrome: Toward an Integration of the Literature

Том 13, Выпуск 1, 2001, 28 pages
DOI: 10.1615/CritRevPhysRehabilMed.v13.i1.20
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Краткое описание

Fibromyalgia syndrome (FMS) is a generalized musculoskeletal pain disorder with multiple functional and psychological problems. Despite extensive efforts during the last 30 years to uncover the etiology, the mechanisms underlying FMS remain elusive. Similarly, no single treatment has proven to be universally effective for FMS. FMS is considered to be a medical enigma, and millions of patients continue to suffer from debilitating pain and disability. The primary objective of this article is to present a thorough review of the current FMS literature. We discuss three primary hypotheses on the pathophysiologic mechanisms: peripheral, psychological, and central. We attempt to integrate the findings and suggest a heuristic model of FMS, integrating the physiological and psychological variables with the predispositional, stress, and time factors associated with FMS. This article also includes a review of clinical trials testing various therapy modalities for FMS. The review emphasizes the importance of understanding the multifactorial nature of FMS; different modalities seem to target different areas of the disorder. We suggest that clinical decisions need to reflect the diversity of the FMS symptom profiles. Interdisciplinary treatments tailored to target a patient's specific needs are likely to improve the clinical efficacy and cost-effectiveness of the therapy.

ЦИТИРОВАНО В
  1. Okifuji Akiko, Bradshaw David H., Olson Chrisana, Evaluating obesity in fibromyalgia: neuroendocrine biomarkers, symptoms, and functions, Clinical Rheumatology, 28, 4, 2009. Crossref

  2. Okifuji Akiko, Hare Bradford D., Do Sleep Disorders Contribute to Pain Sensitivity?, Current Rheumatology Reports, 13, 6, 2011. Crossref

  3. Jones C. Jessie, Rutledge Dana N., Aquino Jordan, Predictors of Physical Performance and Functional Ability in People 50+ With and Without Fibromyalgia, Journal of Aging and Physical Activity, 18, 3, 2010. Crossref

  4. Okifuji Akiko, Hare Bradford D., Sleep Deprivation and Pain, in Sleep Deprivation and Disease, 2014. Crossref

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