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Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
International Journal of Fluid Mechanics Research
ESCI SJR: 0.206 SNIP: 0.446 CiteScore™: 0.5

ISSN Печать: 2152-5102
ISSN Онлайн: 2152-5110

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International Journal of Fluid Mechanics Research

DOI: 10.1615/InterJFluidMechRes.2019025020
Forthcoming Article

Tissue blood perfusion inverse analysis: temperature vs. heat flux approach

Jurij Iljaz
University of Maribor, Faculty of mechanical engineering
Leopold Škerget
University of Maribor, Fculty of mechanical engineeirng
Jure Marn
University of Maribor, Fculty of mechanical engineeirng

Краткое описание

The goal of this study is prediction of blood perfusion through non-homogeneous tissue based on available data of either skin temperature (Dirichlet) or heat flux (Neumann) boundary conditions, and predicting the other. A method proposed for comparing both approaches by solving inverse bio-heat problems is Boundary Element Method employing Levenberg-Marquardt optimization combined with first-order Tikhonov regularization process and L-curve method to determine the optimal value of regularization parameter. Both of proposed approaches, Dirichlet and Neumann, have advantages and disadvantages. Our hypothesis was tested by comparing solutions to existing available results as well as to own results considering different measurement noise levels. Greatest difference between both approaches proposed is the case of low measurement noise where latter gives better agreement with data, especially for deep tissue region. The limitation of proposed method was found to be in the case of high measurement noise where solution was comparable to available measured data in the region close to the boundary. This work should contribute to better understanding of diagnostics of blood perfusion taking advantage of fast measurements of skin temperature and heat flux to determine blood perfusion.