Antitumor Compounds from the Stout Camphor Mushroom <i>Taiwanofungus camphoratus</i> (Higher Basidiomycetes) Spent Culture Broth

Wei  Jia; Yan-Yan  Bai; Zhong  Zhang; Na  Feng; Jie Feng; Mengqiu  Yan; Lina Zhu; Xin-Cheng  Jia; Ming-Dao  Wang; Jingsong Zhang; Hua Fan

doi:10.1615/IntJMedMushrooms.v17.i6.40

International Journal of Medicinal Mushrooms

Главный редактор: Solomon P. Wasser (open in a new tab)

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ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

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Antitumor Compounds from the Stout Camphor Mushroom Taiwanofungus camphoratus (Higher Basidiomycetes) Spent Culture Broth

Том 17, Выпуск 6, 2015, pp. 533-540

DOI: 10.1615/IntJMedMushrooms.v17.i6.40

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Wei Jia
National Engineering Research Center of Edible Fungi, Key Laboratory of Applied Mycological Resources and Utilization of Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding; Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai, 201403, P.R. China

Yan-Yan Bai
Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, National Engineering Research Center of Edible Fungi, National R&D Center for Edible Fungi

Zhong Zhang
National Engineering Research Center of Edible Fungi, Key Laboratory of Applied Mycological Resources and Utilization of Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China

Na Feng
Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, 201403, P.R. China

Jie Feng
Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, 201403, P.R. China

Mengqiu Yan
Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, National Engineering Research Center of Edible Fungi, National R&D Center for Edible Fungi Processing, Shanghai, China

Lina Zhu
National Engineering Research Center of Edible Fungi, Key Laboratory of Applied Mycological Resources and Utilization of Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China

Xin-Cheng Jia
College of Life Sciences, Henan Agricultural University, Zhengzhou, Henan, China

Ming-Dao Wang
College of Life Sciences, Henan Agricultural University, Zhengzhou, Henan, China

Jingsong Zhang
Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences; Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China; National Engineering Research Center of Edible Fungi; National R&D Center for Edible Fungi Processing, Shanghai, 201403, P.R. China

Hua Fan
Institut für Laboratoriumsmedizin Klinische Chemie und Pathobiochemie, Campus Virchow Klinikum, Charite-Universitätsmedizin, Berlin, Germany

Краткое описание

A known compound, 5-(hydroxymethyl) furan-2-carbaldehyde, and a novel compound, 3-isobutyl-1-methoxy-4-(4'-(3-methylbut-2-enyloxy)phenyl)-1H-pyrrole-2,5-dione were isolated from spent broth from submerged cultures of Taiwanofungus camphoratus. Their structures were elucidated by nuclear magnetic resonance (¹H, ¹³C, and 2D) and mass spectra. These compounds inhibited the proliferation of K562 and HepG2 tumor cells in vitro.

Ключевые слова: medicinal mushrooms, Taiwanofungus camphoratus, spent culture broth, 3-isobutyl-1-methoxy-4-(4'-(3-methylbut-2-enyloxy)phenyl)-1H-pyrrole-2, 5-dione, 5-(hydroxymethyl

ЦИТИРОВАНО В

Zhang Jiao-Jiao, Li Ya, Zhou Tong, Xu Dong-Ping, Zhang Pei, Li Sha, Li Hua-Bin, Bioactivities and Health Benefits of Mushrooms Mainly from China, Molecules, 21, 7, 2016. Crossref

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