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International Journal of Medicinal Mushrooms
Главный редактор: Solomon P. Wasser (open in a new tab)

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ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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The Influence of Medicinal Mushroom Preparations on Mouse Tumors

Том 6, Выпуск 2, 2004, 10 pages
DOI: 10.1615/IntJMedMushr.v6.i2.20
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Краткое описание

Extracts from various medicinal mushrooms (Lentinus edodes, Grifola frondosa, and Coriolus (Trametes) versicolor), and particularly their proper blends, are of significant interest in selecting the best of them for treatment, or even prevention, of different pathological aberrations, including cancer. In this study, mushroom preparation effects on the proliferation of tumors and normal cells, respectively, as well as the survival rate of the mice with transplanted tumors, were determined. The incorporation of radioactive 3H thymidine in tumor cells (mouse squamous cell carcinoma [SCCVII], fibrosarcoma [FsaR], and melanoma [B16F10]) was inhibited in the presence of particular mushroom preparations. The effect was dose dependent and was different for tumor cell cultures used. On the other hand, the incorporation of radioactive 3H thymidine in normal Chinese hamster lung fibroblasts (V79 cell) increased, and the effect was generally dose dependent. The application of mushroom preparation to the mice bearing either SCCVII or FsaR tumor could influence their survival. On day 30 after SCCVII tumor cell transplantation, there was a 20% survival rate of mice in the control group, but 60—80% survived if particular mushroom extracts were applied. There were no survivors in the control group on the 36th day, but 40—60% were alive in the experimental groups. Furthermore, there was a 60% survival rate for mice with FsaR tumor when treated with mushroom preparations and a 20% survival rate in the control group on day 36 after tumor cell transplantation.Thus, the findings that the mushroom preparation tested induced a selective inhibition of tumor cell proliferation observed in vitro and a pronounced prolongation of the survival rate of tumor-bearing mice are of particular interest. These findings, together with the data that these compounds are not toxic to the organism, deserve further attention.

ЦИТИРОВАНО В
  1. De Silva Dilani D., Rapior Sylvie, Fons Françoise, Bahkali Ali H., Hyde Kevin D., Medicinal mushrooms in supportive cancer therapies: an approach to anti-cancer effects and putative mechanisms of action, Fungal Diversity, 55, 1, 2012. Crossref

  2. Jakopovic Boris, Oršolić Nada, Jakopovich Ivan, Proteomic Research on the Antitumor Properties of Medicinal Mushrooms, Molecules, 26, 21, 2021. Crossref

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