Доступ предоставлен для: Guest
International Journal of Medicinal Mushrooms
Главный редактор: Solomon P. Wasser (open in a new tab)

Выходит 12 номеров в год

ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Infuence of Culinary-Medicinal Maitake Mushroom, Grifola frondosa (Dicks.: Fr.) S.F. Gray (Aphyllophoromycetideae) Polysaccharides on Gene Expression in Jurkat T Lymphocytes

Том 12, Выпуск 3, 2010, pp. 245-255
DOI: 10.1615/IntJMedMushr.v12.i3.30
Get accessGet access

Краткое описание

The fruiting body of the culinary-medicinal Maitake mushroom Grifola frondosa contains β-glucans that have immunomodulatory effects and potential uses as adjuncts to cancer therapy. Numerous clinical trials are being conducted to assess the benefits of using commercial preparations containing G. frondosa extracts in cancer treatment. We tested a commercially available product containing polysaccharides from the G. frondosa (CGFP) and studied their effect on gene expression in Jurkat T cells. An mRNA differential display was performed to gain insight into the cell response to the substance. HAI1, hnRNP A2/B1, PKC iota, KLRC1, and genes of the ubiquitin system were identified as possible regulators in the mechanism of tumor-suppressor action of CGFP. Real-time polymerase chain reaction (qPCR) was used to investigate the effect of CGFP on cytokine expression in Jurkat T cells. The qPCR results showed that the expression of the gene for IL-5 is increased.

ЦИТИРОВАНО В
  1. Wasser Solomon P., Current findings, future trends, and unsolved problems in studies of medicinal mushrooms, Applied Microbiology and Biotechnology, 89, 5, 2011. Crossref

  2. Xu Wei, Guan Ran, Shi Fushan, Du Aifang, Hu Songhua, Structural analysis and immunomodulatory effect of polysaccharide from Atractylodis macrocephalae Koidz. on bovine lymphocytes, Carbohydrate Polymers, 174, 2017. Crossref

Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции Цены и условия подписки Begell House Контакты Language English 中文 Русский Português German French Spain