Доступ предоставлен для: Guest
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
International Journal of Medicinal Mushrooms
Импакт фактор: 1.423 5-летний Импакт фактор: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Печать: 1521-9437
ISSN Онлайн: 1940-4344

Выпуски:
Том 21, 2019 Том 20, 2018 Том 19, 2017 Том 18, 2016 Том 17, 2015 Том 16, 2014 Том 15, 2013 Том 14, 2012 Том 13, 2011 Том 12, 2010 Том 11, 2009 Том 10, 2008 Том 9, 2007 Том 8, 2006 Том 7, 2005 Том 6, 2004 Том 5, 2003 Том 4, 2002 Том 3, 2001 Том 2, 2000 Том 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v8.i2.50
pages 135-148

Comparative Studies on the Influence of Higher Basidiomycetes Polysaccharide Fractions on Reactive Oxidizing Species Production

Gopalkrishna Lakkireddy
Fungal Biotechnology Research Group, School of Biosciences, University of Westminster, 115, New Cavendish Street, London, W1W 6UW, UK
Tajalli Keshavarz
Fungal Biotechnology Research Group, School of Biosciences, University of Westminster, 115, New Cavendish Street, London, W1W 6UW, UK
Christopher Bucke
Fungal Biotechnology Research Group, School of Biosciences, University of Westminster, 115, New Cavendish Street, London, W1W 6UW, UK

Краткое описание

Mushrooms are greatly prized in oriental cultures because they are known to have more than one active role in traditional medicine. Current practice is to use whole mushroom preparations or simple water extracts. It is assumed that the active polysaccharide fractions are β-(1 3)-glucans. In this work, we have extracted polysaccharides using different solvent systems from dry mycelia of Ganoderma lucidum, G.adspersum, Schizophyllum commune, and Trametes versicolor. The influence of these polysaccharide fractions on reactive oxidizing species production by white blood cells and neutrophils was compared. A novel fluorescent method was used to detect the changes in generation of reactive oxidizing species. The fractions have different and, in some cases, opposing activities on reactive oxidizing species production. Reduction in activity when polysaccharide extracts are used together with N-formyl-methionyl-phenylalanine (FMP), an immune system activator, suggests the active site for these polysaccharides could be the same as that of FMP. This is the first report that polysaccharide fractions from G. adspersum show immunomodulatory properties.


Articles with similar content:

Activity of Extracts from Submerged Cultured Mycelium of Winter Mushroom, Flammulina velutipes (Agaricomycetes), on the Immune System In Vitro
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 1
Gloria Barbosa Sabanero, Victor Tsutsumi Fujiyoshi, Svetlana Kashina, Lerida Liss Flores Villavicencio, Marco Balleza Ordaz, Silvio Zaina, Myrna Sabanero Lopez
Antioxidant and Immunomodulating Activities of Exo-and Endopolysaccharide Fractions from Submerged Mycelia Cultures of Culinary-Medicinal Mushrooms
International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 3
Karthik Marripudi, Cheang Khoo, Sundar Rao Koyyalamudi, Jong Pil Park, Jin Hee Kim, Sang-Chul Jeong, Chi-Hyun Song, J. Margaret Hughes, Trevor Bailey
Chemical Compositions and Macrophage Activation of Polysaccharides from Leon's Mane Culinary-Medicinal Mushroom Hericium erinaceus (Higher Basidiomycetes) in Different Maturation Stages
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 5
Di Wu, Yanfang Liu, Yan Yang, Fengjie Cui, Qiao-Zhen Li, Xia Chen, Shuai Zhou
A Comparative Study of the Antimicrobial, Antioxidant, and Cytotoxic Activities of Methanol Extracts from Fruit Bodies and Fermented Mycelia of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes)
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 5
Tao Yang, Caihong Dong, Tiantian Lian
Chemical Composition and Immunomodulatory Activity of Mycelia of the Hairy Bracket Mushroom, Trametes hirsuta (Higher Basidiomycetes)
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 3
Rongxia Ma, Zhiyi Chen, Rongling Yang, Siyuan Wang, Chunying Yang, Xueming Liu