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Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
International Journal of Medicinal Mushrooms
Импакт фактор: 1.423 5-летний Импакт фактор: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Печать: 1521-9437
ISSN Онлайн: 1940-4344

Выпуски:
Том 21, 2019 Том 20, 2018 Том 19, 2017 Том 18, 2016 Том 17, 2015 Том 16, 2014 Том 15, 2013 Том 14, 2012 Том 13, 2011 Том 12, 2010 Том 11, 2009 Том 10, 2008 Том 9, 2007 Том 8, 2006 Том 7, 2005 Том 6, 2004 Том 5, 2003 Том 4, 2002 Том 3, 2001 Том 2, 2000 Том 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v8.i2.20
pages 101-114

Emerging Antiviral Drugs from Medicinal Mushrooms

Frank F. Piraino
Department. of Visual Sciences, University of Wisconsin Medical School, Madison 517 Rupert Rd., Waunakee, WI. 53597, USA

Краткое описание

Medicinal mushroom antivirals are a diverse group of chemical structures ranging from relatively low molecular weight compounds to high molecular weight carbohydrates and proteins. There is a paucity of information on the manner in which these antivirals interfere with viral replication. Mushroom-derived triterpenes and ubiquitin-associated peptides are examples of novel structures with potentially unique mechanisms of antiviral activity. Studies on these mechanisms will lead to the identification of targets for future drug development. Mushroom antivirals not previously reviewed are examined with these considerations in mind. Also reported here are original observations on the characterization and antiviral properties of a novel antiviral protein, RC 28, isolated from the mushroom Rozites caperatus. Elucidation of the antiviral mechanisms of mushroom antiviral drags are certain to advance the knowledge of viral replication and enhance the contribution of mushroom antivirals for the treatment of viral disease.


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