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Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
International Journal of Physiology and Pathophysiology
SJR: 0.116

ISSN Печать: 2155-014X
ISSN Онлайн: 2155-0158

Archives: Volume 1, 2010 to Volume 9, 2018

International Journal of Physiology and Pathophysiology

DOI: 10.1615/IntJPhysPathophys.v8.i3.70
pages 261-269

Comparison of Spectroscopic Properties of Intraocular Fluid in Patients with Cataract and Primary Open-Angle Glaucoma

S. V. Kolotilov
Ophthalmological clinic "Visiobud plus," Kyiv, Ukraine; Pisargevskiy Institute of physical chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine
V. O. Melnyk
Ophthalmological clinic "Visiobud plus," Kyiv, Ukraine
A. S. Lytvinenko
Ophthalmological clinic "Visiobud plus," Kyiv, Ukraine
S. O. Sotnik
Ophthalmological clinic "Visiobud plus," Kyiv, Ukraine
Olena O. Hurzhii
Ophthalmological clinic "Visiobud plus," Kyiv, Ukraine

Краткое описание

The paper presents a comparison of spectroscopic properties of the intraocular fluid in patients with cataract (60 patients, 60 eyes) and the combination of cataract and primary open angle glaucoma (POAG, 36 patients, 36 eyes). The samples of intraocular fluid were collected during the surgery. Both groups of patients were treated with different types of local drug antihypertensive therapy with different multiplicity and duration of instillation during the preoperative period. The absorption spectra of the intraocular fluid were measured in the wavelength range of 190 – 1100 nm. Two absorption bands were observed with maxima at 202 and 267 nm in the absorption spectrum (the 2nd peak in the spectrum of some samples was shifted to larger wavelengths). The average absorbance of the intraocular fluid at the wavelength of 202 nm in patients without POAG was significantly lower than that in patients with POAG. This difference could be explained with accumulation of metabolites in intraocular fluid of patients with POAG, which in turn may be caused by slowing down the intraocular fluid flow in patients with POAG. Meanwhile, there were no statistically significant differences in average absorbance of the intraocular fluid at the wavelength of 267 nm between the patients of both groups.


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