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ISSN Печать: 1045-4403
ISSN Онлайн: 2162-6502
Indexed in
Targeting MicroRNAs: Promising Future Therapeutics in the Treatment of Allergic Airway Disease
Краткое описание
MicroRNAs (miRNAs) are short noncoding RNAs that control gene expression posttranscriptionally by directly blocking translation of their target mRNAs or by repressing protein production via mRNA destabilization. Investigations into miRNAs began approximately 12 years ago with their discovery in mammalian cells. Still, the involvement of miRNAs in the development of asthma remains unclear, and this topic needs further research to discover various molecular mechanisms responsible for the pathogenesis of asthma and new therapeutic interventions. So far, various miRNAs have been identified in allergic airway disease along with their targets. Our present mini-review highlights the latest information involving the role of miRNAs in asthma.
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Wadhwa Ridhima, Aggarwal Taru, Thapliyal Noopur, Chellappan Dinesh Kumar, Gupta Gaurav, Gulati Monica, Collet Trudi, Oliver Brian, Williams Kylie, Hansbro Philip Michael, Dua Kamal, Maurya Pawan Kumar, Nanoparticle-Based Drug Delivery for Chronic Obstructive Pulmonary Disorder and Asthma, in Nanotechnology in Modern Animal Biotechnology, 2019. Crossref
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Chellappan Dinesh K., Yee Lim W., Xuan Kong Y., Kunalan Kishen, Rou Lim C., Jean Leong S., Ying Lee Y., Wie Lee X., Chellian Jestin, Mehta Meenu, Satija Saurabh, Singh Sachin K., Gulati Monica, Dureja Harish, Da Silva Mateus Webba, Tambuwala Murtaza M., Gupta Gaurav, Paudel Keshav R., Wadhwa Ridhima, Hansbro Philip M., Dua Kamal, Targeting neutrophils using novel drug delivery systems in chronic respiratory diseases, Drug Development Research, 81, 4, 2020. Crossref
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Siddiqui Sana, Johansson Kristina, Joo Alex, Bonser Luke R., Koh Kyung Duk, Le Tonqueze Olivier, Bolourchi Samaneh, Bautista Rodriel A., Zlock Lorna, Roth Theodore L., Marson Alexander, Bhakta Nirav R., Ansel K. Mark, Finkbeiner Walter E., Erle David J., Woodruff Prescott G., Epithelial miR-141 regulates IL-13–induced airway mucus production, JCI Insight, 6, 5, 2021. Crossref
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Laanesoo Anet, Urgard Egon, Periyasamy Kapilraj, Laan Martti, Bochkov Yury A., Aab Alar, Magilnick Nathaniel, Pooga Margus, Gern James E., Johnston Sebastian L., Coquet Jonathan M., Boldin Mark P., Wengel Jesper, Altraja Alan, Bochenek Grazyna, Jakiela Bogdan, Rebane Ana, Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation, Clinical and Translational Medicine, 11, 6, 2021. Crossref
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Liu Juman, Chen Yinhui, Zhang Feng, Peng Xi, Mao Xiaoning, Lu Weihong, Wu Ruijian, Huang Binglong, Bao Yanmin, Ma Lian, Huang Yuge, Zhang Xingliang, Divergent Roles of <b><i>miR-3162-3p</i></b> in Pulmonary Inflammation in Normal and Asthmatic Mice as well as Antagonism of <b><i>miR-3162-3p</i></b> in Asthma Treatment, International Archives of Allergy and Immunology, 181, 8, 2020. Crossref