Выходит 6 номеров в год
ISSN Печать: 1045-4403
ISSN Онлайн: 2162-6502
Indexed in
Computational Modeling of Bone Cells and Their Biomechanical Behaviors in Responses to Mechanical Stimuli
Краткое описание
Bone cells, including osteoblasts, osteoclasts, and osteocytes, have the ability to develop and maintain bone architecture. Although improved experimental testing approaches are increasing our understanding of the complex structures and functions of bone cells and bone, computational models, particularly finite element analyses, are being used to extend this knowledge and to develop a more theoretical understanding of bone cell behaviors. There are many challenges to developing an accurate and validated computational model due to the complex structure and biomechanical behaviors of the bone cells and bone tissue. A better understanding of the geometry and material properties of bone cells and bone will improve our understanding of the bone's biomechanical behaviors. In this review, we summarize and discuss the different geometric representations and material properties that have been used to model the bone cells. The current status of computational models, a comprehensive overview of the modeling methods for the bone cells, and the challenges for validating the models are presented.
-
Zaharie Dan T., Phillips Andrew T.M., A Comparative Study of Continuum and Structural Modelling Approaches to Simulate Bone Adaptation in the Pelvic Construct, Applied Sciences, 9, 16, 2019. Crossref
-
Ti Fei, Chen Xin, Yang Haiqian, Liu Shaobao, Lu Tian Jian, A theory of mechanobiological sensation: strain amplification/attenuation of coated liquid inclusion with surface tension, Acta Mechanica Sinica, 37, 1, 2021. Crossref
-
Wu Xiaogang, Wang Xiyu, Li Chaoxin, Wang Zhaowei, Sun Yuqin, Yan Yang, Qin Yixian, Li Pengcui, Wang Yanqin, Wei Xiaochun, Chen Weiyi, A fluid flow model in the lacunar-canalicular system under the pressure gradient and electrical field driven loads, Applied Mathematics and Mechanics, 43, 6, 2022. Crossref
-
Buccino Federica, Bagherifard Sara, D'Amico Lorenzo, Zagra Luigi, Banfi Giuseppe, Tromba Giuliana, Vergani Laura Maria, Assessing the intimate mechanobiological link between human bone micro-scale trabecular architecture and micro-damages, Engineering Fracture Mechanics, 270, 2022. Crossref