Выходит 6 номеров в год
ISSN Печать: 1543-1649
ISSN Онлайн: 1940-4352
Indexed in
Multiphysics and Multiscale Simulation: Application to a Coupled Model of the Left Ventricle and a Mechanical Heart Valve
Краткое описание
This work combines a number of diverse disciplines (physiology, biomechanics, fluid mechanics, and simulation) in order to develop a predictive model of the behavior of a prosthetic heart valve in vivo. The application of simulation to the study of other cardiovascular problems, such as blood clotting, is also discussed. A commercial, finite volume, computational fluid dynamics (CFD) code (ANSYS/CFX) is used for the three-dimensional (3D) component of the model. A multiscale approach is taken to produce a model of left ventricular function, from the level of the contractile proteins to the resulting ventricular pressure, to provide detailed boundary conditions for the 3D CFD model. We present results from the 3D model and discuss their implications in the context of the cavitation potential of the valve. The results suggest that the use of this approach allows us to address complex cardiovascular problems in greater detail and in a more physiologically orientated manner.
-
Narracott A. J., Zervides C., Diaz V., Rafiroiu D., Lawford P. V., Hose D. R., Analysis of a mechanical heart valve prosthesis and a native venous valve: Two distinct applications of FSI to biomedical applications, International Journal for Numerical Methods in Biomedical Engineering, 26, 3-4, 2010. Crossref
-
Díaz-Zuccarini V., Narracott A.J., Burriesci G., Zervides C., Rafiroiu D., Jones D., Hose D.R., Lawford P.V., Adaptation and development of software simulation methodologies for cardiovascular engineering: present and future challenges from an end-user perspective, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 367, 1898, 2009. Crossref
-
Zhong Qi, Zeng Wen Hua, Huang Xiao Yang, Wang Bo Liang, Numerical Simulation of the Dynamics of Heart Valves: A Literature Review, Applied Mechanics and Materials, 444-445, 2013. Crossref
-
Díaz-Zuccarini Vanessa, Schievano Silvia, Biomedical Imaging and Computational Modeling in Cardiovascular Disease: Patient-Specific Applications Using Numerical Models, in Biomedical Imaging and Computational Modeling in Biomechanics, 4, 2013. Crossref
-
Kheradvar Arash, Pedrizzetti Gianni, Diagnostic Vortex Imaging, in Vortex Formation in the Cardiovascular System, 2012. Crossref