Доступ предоставлен для: Guest
Plasma Medicine

Выходит 4 номеров в год

ISSN Печать: 1947-5764

ISSN Онлайн: 1947-5772

SJR: 0.216 SNIP: 0.263 CiteScore™:: 1.4 H-Index: 24

Indexed in

Atmospheric Pressure Plasma Irradiation on Embryonic Stem Cells: Signals and Differentiation

Том 7, Выпуск 3, 2017, pp. 215-225
DOI: 10.1615/PlasmaMed.2017019653
Get accessDownload

Краткое описание

Mouse embryonic stem cells (ESCs) are pluripotent stem cells (PSCs) derived from pre-implantation embryos. They possess self-renewal properties in vitro and can differentiate into various types of cells. Signaling via extrinsic factors is one of the main factors that determine cell fate during the differentiation of PSCs. For example, fibroblast growth factor (FGF) signal enhances the differentiation of ESCs into ectoderm and neural stem cells in mice and in humans. Recently, reactive oxygen species (ROS) have been reported to regulate various signaling pathways. A large number of reactive species such as ROS and reactive nitrogen species are generated by atmospheric pressure plasma (APP) irradiation. We analyzed the effects of APP irradiation on the maintenance and differentiation of mouse ESCs, focusing on signal control. We found that APP irradiation inhibited the proliferation of mouse ESCs, but did not affect their undifferentiated state. In contrast, APP irradiation did not inhibit the proliferation of embryoid bodies, but did inhibit the differentiation of mouse ESCs to mesoderm and endoderm by inhibiting Wnt signal. APP irradiation enhanced the differentiation to the epiblast, ectoderm, and neuronal lineages by activation of FGF4 signaling. This suggests that the latter effects are caused by the H2O2 generated in the medium by APP irradiation.

ЦИТИРОВАНО В
  1. Application of Plasma to Humans (Blood Coagulation and Regenerative Medicine), in Plasma Medical Science, 2019. Crossref

  2. Veerana Mayura, Lim Jun-Sup, Choi Eun-Ha, Park Gyungsoon, Aspergillus oryzae spore germination is enhanced by non-thermal atmospheric pressure plasma, Scientific Reports, 9, 1, 2019. Crossref

  3. Przekora Agata, Pawlat Joanna, Terebun Piotr, Duday David, Canal Cristina, Hermans Sophie, Audemar Maïté, Labay Cédric, Thomann Jean-Sébastien, Ginalska Grazyna, The effect of low temperature atmospheric nitrogen plasma on MC3T3-E1 preosteoblast proliferation and differentiation in vitro, Journal of Physics D: Applied Physics, 52, 27, 2019. Crossref

  4. Aman Mohammadi Masoud, Ahangari Hossein, Zabihzadeh Khajavi Maryam, Yousefi Mohammad, Scholtz Vladimír, Hosseini Seyede Marzieh, Inactivation of viruses using nonthermal plasma in viral suspensions and foodstuff: A short review of recent studies, Journal of Food Safety, 41, 5, 2021. Crossref

572 Просмотры статей 3461 Загрузка статей Метрики
572 ПРОСМОТРЫ 3461 ЗАГРУЗКИ 4 Crossref ЦИТАТЫ Google
Scholar
ЦИТАТЫ

Статьи с похожим содержанием:

Calcium Ameliorates Renal Cyst Growth in Metanephric Organ Culture: A Morphological Study Journal of Environmental Pathology, Toxicology and Oncology, Vol.31, 2012, issue 3
Surindar Singla, Nidhi Mahajan, Tarundeep Kaur, Veena Puri, Vivekanand Jha, Sanjeev Puri
Arsenic-Mediated Cellular Signal Transduction, Transcription Factor Activation, and Aberrant Gene Expression: Implications in Carcinogenesis Journal of Environmental Pathology, Toxicology and Oncology, Vol.21, 2002, issue 4
Krystyna Frenkel, Chengfeng Yang
Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Protects Aβ1-42-Induced Neurologic Damage in C6 Glial Cells International Journal of Medicinal Mushrooms, Vol.22, 2020, issue 12
Yu Su Shin, Mei Tong He, Chan Hum Park, Ji Myung Choi, Eun Ju Cho
Prostaglandins and the Regulation of Tumor Growth Journal of Environmental Pathology, Toxicology and Oncology, Vol.21, 2002, issue 2
Jane A. Mitchell, Timothy D. Warner, David Bishop-Bailey, Timothy Hla, Sara Calatayud
Protective Effects of Chaga Medicinal Mushroom, Inonotus obliquus (Agaricomycetes), Extract on β-Amyloid-Induced Neurotoxicity in PC12 Cells and Aging Rats: In Vitro and In Vivo Studies International Journal of Medicinal Mushrooms, Vol.23, 2021, issue 9
Yizhou Xin, Xiaoli Zhang, Ying Zhang
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции Цены и условия подписки Begell House Контакты Language English 中文 Русский Português German French Spain