Laser Radiation Control in Photodynamic Therapy of Tumors

N. F. Kovtonyuk; A. V. Ivanov; A. G. Polutov

doi:10.1615/CritRevBiomedEng.v29.i3.120

Critical Reviews™ in Biomedical Engineering

Главный редактор: Anthony J. McGoron (open in a new tab)

Старший редактор: Markad Kamath (open in a new tab)

Ассоциированный редакторs: Garry Duffy (open in a new tab) Alain J. Kassab (open in a new tab) Victoria Timchenko (open in a new tab)

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ISSN Печать: 0278-940X

ISSN Онлайн: 1943-619X

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Laser Radiation Control in Photodynamic Therapy of Tumors

Том 29, Выпуск 3, 2001, pp. 493-501

DOI: 10.1615/CritRevBiomedEng.v29.i3.120

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N. F. Kovtonyuk
"'Kometa' Central Research Institute" Federal State Unitary Enterprise, Academy for Technological Sciences of Russian Federation, Russia

A. V. Ivanov
Laser Tumor Diagnostics and Therapy Laboratory Head at the Scientific Research Institute of Experimental Tumor Diagnostics and Therapy, N. N. Blokhin Russian Oncologic Scientific Center, Russia

A. G. Polutov
Scientific and Technical Promotional Center, "'Kometa' Central Research Institute" Federal State Unitary Enterprise, Russia

Краткое описание

This article presents the ideology and basic principles of designing diagnostic and therapeutic medical systems for treating malignant tumors by means of photosensitizers. The designed system is based on optoelectronic devices, which realize selective laser tumor destruction during photodynamic therapy. A distinguishing feature of this system is that laser-beam formation is performed in real time. This enables one to follow changes in the tumor shape during the treatment. As a result of this study, a photodynamic technique for selective phototreatment was developed and tested. Moreover, We determined light doses for such treatment.

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