Выходит 6 номеров в год
ISSN Печать: 0743-4863
ISSN Онлайн: 2162-660X
Indexed in
Antibody-Based Targeting of Angiogenesis
Краткое описание
Angiogenesisthe sprouting of new blood vessels from pre-existing onesis a characteristic feature of relevant diseases such as cancer, some blinding ocular disorders, rheumatoid arthritis, and psoriasis. This article reviews recent progress in the generation of monoclonal antibodies, which recognize and target new blood vessels in vivo, while sparing mature vessels and healthy tissues. The use of such antibodies as selective "molecular vehicles" is likely to open new important diagnostic and therapeutic opportunities.
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Heinis Christian, Melkko Samu, Demartis Salvatore, Neri Dario, Two General Methods for the Isolation of Enzyme Activities by Colony Filter Screening, Chemistry & Biology, 9, 3, 2002. Crossref
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Heinis Christian, Huber Adrian, Demartis Salvatore, Bertschinger Julian, Melkko Samu, Lozzi Luisa, Neri Paolo, Neri Dario, Selection of catalytically active biotin ligase and trypsin mutants by phage display, Protein Engineering, Design and Selection, 14, 12, 2001. Crossref
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Niesner Uwe, Halin Cornelia, Lozzi Luisa, Günthert Maja, Neri Paolo, Wunderli-Allenspach Heidi, Zardi Luciano, Neri Dario, Quantitation of the Tumor-Targeting Properties of Antibody Fragments Conjugated to Cell-Permeating HIV-1 TAT Peptides, Bioconjugate Chemistry, 13, 4, 2002. Crossref
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