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Critical Reviews™ in Therapeutic Drug Carrier Systems
Главный редактор: Mandip Sachdeva Singh (open in a new tab)

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ISSN Печать: 0743-4863

ISSN Онлайн: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

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Nano-Aggregates: Emerging Delivery Tools for Tumor Therapy

Том 30, Выпуск 6, 2013, pp. 535-563
DOI: 10.1615/CritRevTherDrugCarrierSyst.2013007706
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Краткое описание

A plethora of formulation techniques have been reported in the literature for site-specific targeting of water-soluble and -insoluble anticancer drugs. Along with other vesicular and particulate carrier systems, nano-aggregates have recently emerged as a novel supramolecular colloidal carrier with promise for using poorly water-soluble drugs in molecular targeted therapies. Nano-aggregates possess some inherent properties such as size in the nanometers, high loading efficiency, and in vivo stability. Nano-aggregates can provide site-specific drug delivery via either a passive or active targeting mechanism. Nano-aggregates are formed from a polymer-drug conjugated amphiphilic block copolymer. They are suitable for encapsulation of poorly water-soluble drugs by covalent conjugation as well as physical encapsulation. Because of physical encapsulation, a maximum amount of drug can be loaded in nano-aggregates, which helps to achieve a sufficiently high drug concentration at the target site. Active transport can be achieved by conjugating a drug with vectors or ligands that bind specifically to receptors being overexpressed in the tumor cells. In this review, we explore synthesis and tumor targeting potential of nano-aggregates with active and passive mechanisms, and we discuss various characterization parameters, ex vivo studies, biodistribution studies, clinical trials, and patents.

ЦИТИРОВАНО В
  1. Zhu Wenxia, Song Zhimei, Wei Peng, Meng Ning, Teng Fangfang, Yang Fengying, Liu Na, Feng Runliang, Y-shaped biotin-conjugated poly (ethylene glycol)–poly (epsilon-caprolactone) copolymer for the targeted delivery of curcumin, Journal of Colloid and Interface Science, 443, 2015. Crossref

  2. Subudhi M., Jain Ankit, Jain Ashish, Hurkat Pooja, Shilpi Satish, Gulbake Arvind, Jain Sanjay, Eudragit S100 Coated Citrus Pectin Nanoparticles for Colon Targeting of 5-Fluorouracil, Materials, 8, 3, 2015. Crossref

  3. Jain Ankit, Jain Sanjay K., Environmentally Responsive Chitosan-Based Nanocarriers (CBNs), in Handbook of Polymers for Pharmaceutical Technologies, 2015. Crossref

  4. Mahmood Kashif, Zia Khalid Mahmood, Zuber Mohammad, Salman Mahwish, Anjum Muhammad Naveed, Recent developments in curcumin and curcumin based polymeric materials for biomedical applications: A review, International Journal of Biological Macromolecules, 81, 2015. Crossref

  5. Balan Vera, Verestiuc Liliana, Butnaru Maria, Bredetean Ovidiu, Knieling Laura, Munteanu Anca, Design and characterization of biotinylated magnetic nanocapsules for breast cancer applications, 2015 E-Health and Bioengineering Conference (EHB), 2015. Crossref

  6. Jain Ankit, Jain Sanjay K., In vitro release kinetics model fitting of liposomes: An insight, Chemistry and Physics of Lipids, 201, 2016. Crossref

  7. Jain Ankit, Jain Sanjay K., Application Potential of Engineered Liposomes in Tumor Targeting, in Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics, 2017. Crossref

  8. Conte Raffaele, De Luca Ilenia, Valentino Anna, Di Salle Anna, Calarco Anna, Riccitiello Francesco, Peluso Gianfranco, Recent advances in “bioartificial polymeric materials” based nanovectors, Physical Sciences Reviews, 2, 4, 2017. Crossref

  9. Mehta Piyush, Bothiraja C., Kadam Shivajirao, Pawar Atmaram, Potential of dry powder inhalers for tuberculosis therapy: facts, fidelity and future, Artificial Cells, Nanomedicine, and Biotechnology, 46, sup3, 2018. Crossref

  10. Maiti Santanu, Paira Priyankar, Biotin conjugated organic molecules and proteins for cancer therapy: A review, European Journal of Medicinal Chemistry, 145, 2018. Crossref

  11. Lü Shaowa, Su Hong, Sun Shuang, Guo Yuyan, Liu Ting, Ping Yang, Li Yongji, Isolation and characterization of nanometre aggregates from a Bai-Hu-Tang decoction and their antipyretic effect, Scientific Reports, 8, 1, 2018. Crossref

  12. Sahu Kantrol Kumar, Kaurav Monika, Pandey Ravi Shankar, Chylomicron mimicking solid lipid nanoemulsions encapsulated enteric minicapsules targeted to colon for immunization against hepatitis B, International Immunopharmacology, 66, 2019. Crossref

  13. Sahu Kantrol Kumar, Pandey Ravi Shankar, Development and characterization of HBsAg-loaded Eudragit nanoparticles for effective colonic immunization, Pharmaceutical Development and Technology, 24, 2, 2019. Crossref

  14. Prajapati Shiv Kumar, Jain Ankit, Jain Aakanchha, Jain Sourabh, Biodegradable polymers and constructs: A novel approach in drug delivery, European Polymer Journal, 120, 2019. Crossref

  15. Tiwari Ankita, Saraf Shivani, Jain Ankit, Panda Pritish K., Verma Amit, Jain Sanjay K., Basics to advances in nanotherapy of colorectal cancer, Drug Delivery and Translational Research, 10, 2, 2020. Crossref

  16. Soni Vandana, A Novel Strategy for the Delivery of Doxorubicin to Reduce Cardiotoxicity, Pharmacy & Pharmacology International Journal, 4, 7, 2016. Crossref

  17. Kou Zhongyang, Wang Xin, Yuan Renshun, Chen Huabin, Zhi Qiaoming, Gao Ling, Wang Bin, Guo Zhaoji, Xue Xiaofeng, Cao Wei, Guo Liang, A promising gene delivery system developed from PEGylated MoS2 nanosheets for gene therapy, Nanoscale Research Letters, 9, 1, 2014. Crossref

  18. Borderwala Kruti, Rathod Sachin, Yadav Sarita, Vyas Bhavin, Shah Pranav, Eudragit S-100 Surface Engineered Nanostructured Lipid Carriers for Colon Targeting of 5-Fluorouracil: Optimization and In Vitro and In Vivo Characterization, AAPS PharmSciTech, 22, 6, 2021. Crossref

  19. Saraf Shivani, Jain Ankit, Tiwari Ankita, Verma Amit, Jain Sanjay K., Engineered liposomes bearing camptothecin analogue for tumour targeting: in vitro and ex-vivo studies, Journal of Liposome Research, 31, 4, 2021. Crossref

  20. Balan Vera, Redinciuc Valentina, Tudorachi Nita, Verestiuc Liliana, Biotinylated N-palmitoyl chitosan for design of drug loaded self-assembled nanocarriers, European Polymer Journal, 81, 2016. Crossref

  21. Carvalho Josué, Lopes-Nunes Jéssica, Vialet Brune, Rosado Tiago, Gallardo Eugenia, Vale João, Eloy Catarina, Ferreira Sofia, Palmeira-de-Oliveira Rita, Campello Maria Paula Cabral, Paulo António, Barthélémy Philippe, Mergny Jean-Louis, Salgado Gilmar F., Queiroz João A., Ellington Andrew D., Cruz Carla, Nanoaggregate-forming lipid-conjugated AS1411 aptamer as a promising tumor-targeted delivery system of anticancer agents in vitro, Nanomedicine: Nanotechnology, Biology and Medicine, 36, 2021. Crossref

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