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Critical Reviews™ in Immunology

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ISSN Печать: 1040-8401

ISSN Онлайн: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

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The Adhesion- and Degranulation-Promoting Adaptor Protein and Its Role in the Modulation of Experimental Autoimmune Encephalomyelitis

Том 35, Выпуск 1, 2015, pp. 1-14
DOI: 10.1615/CritRevImmunol.2014012162
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Краткое описание

Adaptor proteins mediate protein−protein interactions in signal transduction cascades. These signaling molecules are organized in multimolecular complexes that translate information from cell surface receptors into cellular responses. The cytosolic adhesion- and degranulation-promoting adaptor protein (ADAP) is expressed in T cells, natural killer cells, myeloid cells, and platelets. Here we summarize the data about the function of ADAP in these cells with respect to their contribution to the pathogenesis of experimental autoimmune encephalomyelitis. We discuss possible mechanisms of strongly attenuated experimental autoimmune encephalomyelitis in ADAP-deficient mice.

Ключевые слова: EAE, CNS, autoimmunity, adaptor protein, ADAP
ЦИТИРОВАНО В
  1. Kuropka Benno, Schraven Burkhart, Kliche Stefanie, Krause Eberhard, Freund Christian, Tyrosine-phosphorylation of the scaffold protein ADAP and its role in T cell signaling, Expert Review of Proteomics, 13, 6, 2016. Crossref

  2. Thiere Marlen, Kliche Stefanie, Müller Bettina, Teuber Jan, Nold Isabell, Stork Oliver, Integrin Activation Through the Hematopoietic Adapter Molecule ADAP Regulates Dendritic Development of Hippocampal Neurons, Frontiers in Molecular Neuroscience, 9, 2016. Crossref

  3. Kasirer-Friede Ana, ADAP, in Encyclopedia of Signaling Molecules, 2018. Crossref

  4. Kasirer-Friede Ana, ADAP, in Encyclopedia of Signaling Molecules, 2016. Crossref

  5. Rudolph Jochen, Meinke Clara, Voss Martin, Guttek Karina, Kliche Stefanie, Reinhold Dirk, Schraven Burkhart, Reinhold Annegret, Immune Cell-Type Specific Ablation of Adapter Protein ADAP Differentially Modulates EAE, Frontiers in Immunology, 10, 2019. Crossref

  6. Dadwal Nirdosh, Mix Charlie, Reinhold Annegret, Witte Amelie, Freund Christian, Schraven Burkhart, Kliche Stefanie, The Multiple Roles of the Cytosolic Adapter Proteins ADAP, SKAP1 and SKAP2 for TCR/CD3 -Mediated Signaling Events, Frontiers in Immunology, 12, 2021. Crossref

  7. Rudolph Jochen Michael, Guttek Karina, Weitz Gabriele, Meinke Clara Antonia, Kliche Stefanie, Reinhold Dirk, Schraven Burkhart, Reinhold Annegret, Characterization of Mice with a Platelet-Specific Deletion of the Adapter Molecule ADAP, Molecular and Cellular Biology, 39, 9, 2019. Crossref

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