Доступ предоставлен для: Guest
Critical Reviews™ in Immunology

Выходит 6 номеров в год

ISSN Печать: 1040-8401

ISSN Онлайн: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Critical Roles of Toll-Like Receptors in Host Defense

Том 20, Выпуск 5, 2000, 14 pages
DOI: 10.1615/CritRevImmunol.v20.i5.30
Get accessGet access

Краткое описание

Drosophila Toll is involved not only in dorsoventral patterning of embryos but also in immune responses to microbial infection. Several Toll-like receptors (TLRs) have also been identified in mammals. They are expressed on macrophages or dendritic cells (DCs), which are essential sentinels for innate immunity. These cells utilize TLRs as a recognition and signal transducing receptor for microbial molecular components. The most characterized mammalian TLR, TLR4, is a receptor for lipopolysaccharides (LPS). TLR2 recognizes other components, such as peptideglycans (PGN). This recognition, called pattern recognition, is essential for the establishment of innate immunity, which is the basis for host defense. In this article, we review recent findings about this expanding receptor family.

ЦИТИРОВАНО В
  1. Nagano F., Kaneko T., Yoshinaga Y., Ukai T., Kuramoto A., Nakatsu S., Oshino K., Ichimura I., Hara Y., Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction, Journal of Periodontal Research, 48, 4, 2013. Crossref

  2. Im Seung-Soon, Yousef Leyla, Blaschitz Christoph, Liu Janet Z., Edwards Robert A., Young Stephen G., Raffatellu Manuela, Osborne Timothy F., Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein-1a, Cell Metabolism, 13, 5, 2011. Crossref

  3. Aleyas Abi G., Han Young Woo, Patil Ajit Mahadev, Kim Seong Bum, Kim Koanhoi, Eo Seong Kug, Impaired cross-presentation of CD8α+CD11c+dendritic cells by Japanese encephalitis virus in a TLR2/MyD88 signal pathway-dependent manner, European Journal of Immunology, 42, 10, 2012. Crossref

  4. Mori Y., Yoshimura A., Ukai T., Lien E., Espevik T., Hara Y., Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis, Oral Microbiology and Immunology, 18, 1, 2003. Crossref

  5. Cutler Christopher W., Jotwani Ravi, Antigen-presentation and the role of dendritic cells in periodontitis, Periodontology 2000, 35, 1, 2004. Crossref

  6. Deehan Maureen R., Goodridge Helen S., Blair Derek, Lochnit Gunter, Dennis Roger D., Geyer Rudolf, Harnett Margaret M., Harnett William, Immunomodulatory properties of Ascaris suum glycosphingolipids - phosphorylcholine and non-phosphorylcholine-dependent effects, Parasite Immunology, 24, 9-10, 2002. Crossref

  7. Koutouzis Theofilos, Catania Dominick, Neiva Kathleen, Wallet Shannon M., Innate Immune Receptor Expression in Peri-Implant Tissues of Patients With Different Susceptibility to Periodontal Diseases, Journal of Periodontology, 84, 2, 2013. Crossref

  8. Guirado Evelyn, Schlesinger Larry S., Kaplan Gilla, Macrophages in tuberculosis: friend or foe, Seminars in Immunopathology, 35, 5, 2013. Crossref

  9. Heine Holger, TLRs, NLRs and RLRs: Innate sensors and their impact on allergic diseases – A current view, Immunology Letters, 139, 1-2, 2011. Crossref

  10. de Vries I. Jolanda M., Tel Jurjen, Benitez-Ribas Daniel, Torensma Ruurd, Figdor Carl G., Prophylactic vaccines mimic synthetic CpG oligonucleotides in their ability to modulate immune responses, Molecular Immunology, 48, 6-7, 2011. Crossref

  11. Kadowaki Takeshi, Yasui Yasumasa, Nishimiya Osamu, Takahashi Yukinori, Kohchi Chie, Soma Gen-Ichiro, Inagawa Hiroyuki, Orally administered LPS enhances head kidney macrophage activation with down-regulation of IL-6 in common carp (Cyprinus carpio), Fish & Shellfish Immunology, 34, 6, 2013. Crossref

  12. Barr Tom A., Brown Sheila, Ryan Gemma, Zhao Jiexin, Gray David, TLR-mediated stimulation of APC: Distinct cytokine responses of B cells and dendritic cells, European Journal of Immunology, 37, 11, 2007. Crossref

  13. Muriel Pablo, NF-κB in liver diseases: a target for drug therapy, Journal of Applied Toxicology, 29, 2, 2009. Crossref

  14. Yamamoto Masato, Curiel David T, Current Issues and Future Directions of Oncolytic Adenoviruses, Molecular Therapy, 18, 2, 2010. Crossref

  15. Hoth J. Jason, Hudson William P., Brownlee Noel A., Yoza Barbara K., Hiltbold Elizabeth M., Meredith J. Wayne, McCall Charles E., TOLL-LIKE RECEPTOR 2 PARTICIPATES IN THE RESPONSE TO LUNG INJURY IN A MURINE MODEL OF PULMONARY CONTUSION, Shock, 28, 4, 2007. Crossref

  16. Sathe Ameya, Patgaonkar Mandar S., Bashir Tahir, Reddy Kudumula Venkata Rami, MicroRNA Let-7f: A Novel Regulator of Innate Immune Response in Human Endocervical Cells, American Journal of Reproductive Immunology, 71, 2, 2014. Crossref

  17. Eskan Mehmet A., Rose Beate G., Benakanakere Manjunatha R., Zeng Qun, Fujioka Daisuke, Martin Michael H., Lee Menq-Jer, Kinane Denis F., TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells, European Journal of Immunology, 38, 4, 2008. Crossref

  18. Baranov Maksim V, Beest Martin ter, Bogaart Geert van den, Reaching for far-flung antigen: How solid-core podosomes of dendritic cells transform into protrusive structures, Communicative & Integrative Biology, 7, 5, 2014. Crossref

  19. Gröbner Sabine, Lukowski Robert, Autenrieth Ingo B., Ruth Peter, Lipopolysaccharide induces cell volume increase and migration of dendritic cells, Microbiology and Immunology, 58, 1, 2014. Crossref

  20. Horiuchi Yasuhiro, Bae SangJae, Katayama Ichiro, Oshikawa Tetsuya, Okamoto Masato, Sato Mitsunobu, Lipoteichoic acid-related molecule derived from the streptococcal preparation, OK-432, which suppresses atopic dermatitis-like lesions in NC/Nga mice, Archives of Dermatological Research, 298, 4, 2006. Crossref

  21. ZHANG Q., FENG X., NIE W., GOLENBOCK D. T., MAYANJA-KIZZA H., TZIPORI S., FENG H., MyD88-dependent pathway is essential for the innate immunity to Enterocytozoon bieneusi, Parasite Immunology, 33, 4, 2011. Crossref

  22. Ren Chunhua, Chen Ting, Jiang Xiao, Wang Yanhong, Hu Chaoqun, Identification and functional characterization of a novel ferritin subunit from the tropical sea cucumber, Stichopus monotuberculatus, Fish & Shellfish Immunology, 38, 1, 2014. Crossref

  23. Amcheslavsky Alla, Hemmi Hiroaki, Akira Shizuo, Bar-Shavit Zvi, Differential Contribution of Osteoclast- and Osteoblast-Lineage Cells to CpG-Oligodeoxynucleotide (CpG-ODN) Modulation of Osteoclastogenesis, Journal of Bone and Mineral Research, 20, 9, 2005. Crossref

  24. Ren Chunhua, Chen Ting, Jiang Xiao, Luo Xing, Wang Yanhong, Hu Chaoqun, The first echinoderm gamma-interferon-inducible lysosomal thiol reductase (GILT) identified from sea cucumber (Stichopus monotuberculatus), Fish & Shellfish Immunology, 42, 1, 2015. Crossref

  25. Wachi Takanori, Shuto Takahiro, Shinohara Yoshinori, Matono Yoshinari, Makihira Seicho, Release of titanium ions from an implant surface and their effect on cytokine production related to alveolar bone resorption, Toxicology, 327, 2015. Crossref

  26. Huang Hao, Park Cheol Kyu, Ryu Ji Yoon, Chang Eun-Ju, Lee Youngkyun, Kang Sam Sik, Kim Hong-Hee, Expression profiling of lipopolysaccharide target genes in RAW264.7 cells by oligonucleotide microarray analyses, Archives of Pharmacal Research, 29, 10, 2006. Crossref

  27. Murata Yukie, Amao Michiko, Yoneda Junya, Hamuro Junji, Intracellular thiol redox status of macrophages directs the Th1 skewing in thioredoxin transgenic mice during aging, Molecular Immunology, 38, 10, 2002. Crossref

  28. Quan Song-Hua, Zhang Yu-Lian, Han Doo Hee, Iwakura Yoichiro, Rhee Chae-Seo, Contribution of interleukin 17A to the development and regulation of allergic inflammation in a murine allergic rhinitis model, Annals of Allergy, Asthma & Immunology, 108, 5, 2012. Crossref

  29. Pannacci Marilou, Lucini Valeria, Colleoni Federica, Martucci Cataldo, Grosso Silvia, Sacerdote Paola, Scaglione Francesco, Panax ginseng C.A. Mayer G115 modulates pro-inflammatory cytokine production in mice throughout the increase of macrophage toll-like receptor 4 expression during physical stress, Brain, Behavior, and Immunity, 20, 6, 2006. Crossref

  30. Murata Yukie, Shimamura Toshiro, Tagami Tomoyuki, Takatsuki Fumihiko, Hamuro Junji, The skewing to Th1 induced by lentinan is directed through the distinctive cytokine production by macrophages with elevated intracellular glutathione content, International Immunopharmacology, 2, 5, 2002. Crossref

  31. Delvecchio Francesca Romana, Vadrucci Elisa, Cavalcanti Elisabetta, De Santis Stefania, Kunde Dale, Vacca Michele, Myers Jay, Allen Frederick, Bianco Giusy, Huang Alex Y., Monsurro Vladia, Santino Angelo, Chieppa Marcello, Polyphenol administration impairs T-cell proliferation by imprinting a distinct dendritic cell maturational profile, European Journal of Immunology, 45, 9, 2015. Crossref

  32. Wang Jun, Zhao Hui, Mao-Ying Qi-Liang, Cao Xiao-Ding, Wang Yan-Qing, Wu Gen-Cheng, Electroacupuncture downregulates TLR2/4 and pro-inflammatory cytokine expression after surgical trauma stress without adrenal glands involvement, Brain Research Bulletin, 80, 1-2, 2009. Crossref

  33. Gabehart Kelsa, Correll Kelly A., Loader Joan E., White Carl W., Dakhama Azzeddine, The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4, Respiratory Research, 16, 1, 2015. Crossref

  34. Weeratna Risini D., Makinen Shawn R., McCluskie Michael J., Davis Heather L., TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848), Vaccine, 23, 45, 2005. Crossref

  35. Kimura Tomomi, Shibata Yoko, Yamauchi Keiko, Igarashi Akira, Inoue Sumito, Abe Shuichi, Fujita Kazuhiro, Uosaki Yoichi, Kubota Isao, Oxidized Phospholipid, 1-Palmitoyl-2-(9′-Oxo-Nonanoyl)-Glycerophosphocholine (PON-GPC), Produced in the Lung Due to Cigarette Smoking, Impairs Immune Function in Macrophages, Lung, 190, 2, 2012. Crossref

  36. Park Mi-Young, Carnosic acid disrupts toll-like receptor 2 signaling pathway in Pam3CSK4-stimulated macrophages, Toxicology and Environmental Health Sciences, 7, 3, 2015. Crossref

  37. Mizutani Akiei, Shaheen Victoria M., Yoshida Hideo, Akaogi Jun, Kuroda Yoshiki, Nacionales Dina C., Yamasaki Yoshioki, Hirakata Michito, Ono Nobutaka, Reeves Westley H., Satoh Minoru, Pristane-induced autoimmunity in germ-free mice, Clinical Immunology, 114, 2, 2005. Crossref

  38. Rastogi D., Ratner A.J., Prince A., Host–bacterial interactions in the initiation of inflammation, Paediatric Respiratory Reviews, 2, 3, 2001. Crossref

  39. Makihira Seicho, Mine Yuichi, Nikawa Hiroki, Shuto Takahiro, Iwata Satoshi, Hosokawa Ryuji, Kamoi Kohei, Okazaki Shota, Yamaguchi Yu, Titanium ion induces necrosis and sensitivity to lipopolysaccharide in gingival epithelial-like cells, Toxicology in Vitro, 24, 7, 2010. Crossref

  40. Ozaki Yukio, Ukai Takashi, Yamaguchi Masayuki, Yokoyama Miho, Ayón Haro Esperanza R., Yoshimoto Mayumi, Kaneko Takashi, Yoshinaga Miho, Nakamura Hirotaka, Shiraishi Chiaki, Hara Yoshitaka, Locally administered T cells from mice immunized with lipopolysaccharide (LPS) accelerate LPS-induced bone resorption, Bone, 44, 6, 2009. Crossref

  41. Strindelius Lena, Filler Malin, Sjöholm Ingvar, Mucosal immunization with purified flagellin from Salmonella induces systemic and mucosal immune responses in C3H/HeJ mice, Vaccine, 22, 27-28, 2004. Crossref

  42. Szabo Gyongyi, Dolganiuc Angela, Hepatitis C and Innate Immunity: Recent Advances, Clinics in Liver Disease, 12, 3, 2008. Crossref

  43. Jiang Hong-Wei, Zhang Wei, Ren Bang-Peng, Zeng Jin-Feng, Ling Jun-Qi, Expression of Toll Like Receptor 4 in Normal Human Odontoblasts and Dental Pulp Tissue, Journal of Endodontics, 32, 8, 2006. Crossref

  44. Ernst Robert K., Guina Tina, Miller Samuel I., Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity, Microbes and Infection, 3, 14-15, 2001. Crossref

  45. Zhang Ping, Katz Jenny, Michalek Suzanne M., Glycogen synthase kinase-3β (GSK3β) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice, Molecular Immunology, 46, 4, 2009. Crossref

  46. Gumperz Jenny E, Brenner Michael B, CD1-specific T cells in microbial immunity, Current Opinion in Immunology, 13, 4, 2001. Crossref

  47. Rasley Amy, Anguita Juan, Marriott Ian, Borrelia burgdorferi induces inflammatory mediator production by murine microglia, Journal of Neuroimmunology, 130, 1-2, 2002. Crossref

  48. Lee Mi Jin, Park Mi-Young, Kim Soon-Kyung, Aloe-emodin inhibits Pam3CSK4-induced MAPK and NF-κB signaling through TLR2 in macrophages, Journal of Nutrition and Health, 49, 4, 2016. Crossref

  49. Slotta J. E., Braun O. Ö., Menger M. D., Thorlacius H., Capture of platelets to the endothelium of the femoral vein is mediated by CD62P and CD162, Platelets, 20, 7, 2009. Crossref

  50. Qian Jing, Ren Chunhua, Xia Jianjun, Chen Ting, Yu Zonghe, Hu Chaoqun, Discovery, structural characterization and functional analysis of alpha-2-macroglobulin, a novel immune-related molecule from Holothuria atra, Gene, 585, 2, 2016. Crossref

  51. Seo Dong-Won, Cho Yong-Il, Gu Suna, Kim Da-Hee, Park Jung-Hee, Yi Young-Joo, Lee Sang-Myeong, A hot water extract ofAralia cordataactivates bone marrow-derived macrophages via a myeloid differentiation protein 88-dependent pathway and protects mice from bacterial infection, Microbiology and Immunology, 60, 5, 2016. Crossref

  52. Funakoshi-Tago Megumi, Ohsawa Kentaro, Ishikawa Toshiyuki, Nakamura Fumika, Ueda Fumihito, Narukawa Yuji, Kiuchi Fumiyuki, Tamura Hiroomi, Tago Kenji, Kasahara Tadashi, Inhibitory effects of flavonoids extracted from Nepalese propolis on the LPS signaling pathway, International Immunopharmacology, 40, 2016. Crossref

  53. Enkhbaatar Perenlei, Nelson Christina, Salsbury John R., Carmical Joseph R., Torres Karen E. O., Herndon David, Prough Donald S., Luan Liming, Sherwood Edward R., Tuckermann Jan Peter, Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A, PLOS ONE, 10, 12, 2015. Crossref

  54. Hung Wei-Shan, Ling Pin, Cheng Ju-Chien, Chang Shy-Shin, Tseng Ching-Ping, Disabled-2 is a negative immune regulator of lipopolysaccharide-stimulated Toll-like receptor 4 internalization and signaling, Scientific Reports, 6, 1, 2016. Crossref

  55. Wilson Malinda, Widdicombe Jonathan H., Gohil Kishorchandra, Burtis Kenneth C., Reznick Abraham Z., Cross Carroll E., Eiserich Jason P., AreDrosophilaa Useful Model for Understanding the Toxicity of Inhaled Oxidative Pollutants: A Review, Inhalation Toxicology, 17, 13, 2005. Crossref

  56. Qian Jing, Ren Chunhua, Chen Ting, Xia Jianjun, Yu Zonghe, Gao Yan, Hu Chaoqun, Identification and functional characterization of first alpha‐2‐macroglobulin in sea cucumbers, Aquaculture Research, 48, 5, 2017. Crossref

  57. Malgorzata-Miller Gosia, Heinbockel Lena, Brandenburg Klaus, van der Meer Jos W. M., Netea Mihai G., Joosten Leo A. B., Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications, Scientific Reports, 6, 1, 2016. Crossref

  58. Frost Robert A., Nystrom Gerald J., Lang Charles H., Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 283, 3, 2002. Crossref

  59. Frleta Davor, Noelle Randolph J., Wade William F., CD40-mediated up-regulation of Toll-like receptor 4-MD2 complex on the surface of murine dendritic cells, Journal of Leukocyte Biology, 74, 6, 2003. Crossref

  60. Vieira Frederico, Kung Johannes W., Bhatti Faizah, Structure, genetics and function of the pulmonary associated surfactant proteins A and D: The extra-pulmonary role of these C type lectins, Annals of Anatomy - Anatomischer Anzeiger, 211, 2017. Crossref

  61. Murata Yukie, Yamashita Akira, Saito Takashi, Sugamura Kazuo, Hamuro Junji, The conversion of redox status of peritoneal macrophages during pathological progression of spontaneous inflammatory bowel disease in Janus family tyrosine kinase 3–/– and IL‐2 receptor γ–/– mice, International Immunology, 14, 6, 2002. Crossref

  62. Kaushik Deepak Kumar, Gupta Malvika, Kumawat Kanhaiya Lal, Basu Anirban, Wang Tian, NLRP3 Inflammasome: Key Mediator of Neuroinflammation in Murine Japanese Encephalitis, PLoS ONE, 7, 2, 2012. Crossref

  63. Billack Blase, Heck Diane E., Mariano Thomas M., Gardner Carol R., Sur Runa, Laskin Debra L., Laskin Jeffrey D., Induction of cyclooxygenase-2 by heat shock protein 60 in macrophages and endothelial cells, American Journal of Physiology-Cell Physiology, 283, 4, 2002. Crossref

  64. Kim Yun Jeong, Kim Jeong-Hee, Lee Kwang-Jun, Choi Myung-Min, Kim Yeon Hee, Rhie Gi-eun, Yoo Cheon-Kwon, Cha Kiweon, Shin Na-Ri, Johnson Eric A., Botulinum Neurotoxin Type A Induces TLR2-Mediated Inflammatory Responses in Macrophages, PLOS ONE, 10, 4, 2015. Crossref

  65. Murata Yukie, Shimamura Toshiro, Hamuro Junji, The polarization of Th1/Th2 balance is dependent on the intracellular thiol redox status of macrophages due to the distinctive cytokine production, International Immunology, 14, 2, 2002. Crossref

  66. Xiao Xingxing, Zhang Yun, Wei Qiaolin, Yin Xiangping, Flagellin FljB as an adjuvant to the recombinant adenovirus rabies glycoprotein vaccine increases immune responses against rabies in mice, Archives of Virology, 162, 9, 2017. Crossref

  67. Anderson Charles F., Gerber Jeffrey S., Mosser David M., Modulating macrophage function with IgG immune complexes, Journal of Endotoxin Research, 8, 6, 2002. Crossref

  68. Kim Sung Ouk, Ono Koh, Han Jiahuai, Apoptosis by pan-caspase inhibitors in lipopolysaccharide-activated macrophages, American Journal of Physiology-Lung Cellular and Molecular Physiology, 281, 5, 2001. Crossref

  69. Liu Q., Hamblin M. R., Macrophage-Targeted Photodynamic Therapy: Scavenger Receptor Expression and Activation State, International Journal of Immunopathology and Pharmacology, 18, 3, 2005. Crossref

  70. Moretto Magali M., Khan Imtiaz A., Weiss Louis M., Knoll Laura J., Gastrointestinal Cell Mediated Immunity and the Microsporidia, PLoS Pathogens, 8, 7, 2012. Crossref

  71. Yamamoto Kana, Furuya Kanon, Yamada Kazuki, Takahashi Fuka, Hamajima Chisato, Tanaka Sachi, Enhancement of natural killer activity and IFN-γ production in an IL-12-dependent manner by a Brassica rapa L., Bioscience, Biotechnology, and Biochemistry, 82, 4, 2018. Crossref

  72. Kim Min-Sung, Byun Minji, Oh Byung-Ha, Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster, Nature Immunology, 4, 8, 2003. Crossref

  73. Tarabees R., Hill D., Rauch C., Barrow P. A., Loughna P. T., Endotoxin transiently inhibits protein synthesis through Akt and MAPK mediating pathways in C2C12 myotubes, American Journal of Physiology-Cell Physiology, 301, 4, 2011. Crossref

  74. Feingold Kenneth R., Shigenaga Judy K., Kazemi Mahmood R., McDonald Carol M., Patzek Sophie M., Cross Andrew S., Moser Arthur, Grunfeld Carl, Mechanisms of triglyceride accumulation in activated macrophages, Journal of Leukocyte Biology, 92, 4, 2012. Crossref

  75. Ryu Yun-Kyoung, Lee Mi-Hee, Lee Jiyoung, Lee Jae-Wook, Jang Su-Jin, Kang Joo-Hyun, Moon Eun-Yi, γ-Irradiated cancer cells promote tumor growth by activation of Toll-like receptor 1-mediated inducible nitric oxide synthase in macrophages, Journal of Leukocyte Biology, 97, 4, 2015. Crossref

  76. Nathan Carl, Ding Aihao, TREM-1: A new regulator of innate immunity in sepsis syndrome, Nature Medicine, 7, 5, 2001. Crossref

  77. Pereira João Pedro, Girard Robert, Chaby Richard, Cumano Ana, Vieira Paulo, Monoallelic expression of the murine gene encoding Toll-like receptor 4, Nature Immunology, 4, 5, 2003. Crossref

  78. Ferraris Davide, Miggiano Riccardo, Rossi Franca, Rizzi Menico, Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets, Pathogens, 7, 1, 2018. Crossref

  79. Cai Xiaoyu, Zhang Lingling, Wei Wei, Regulatory B cells in inflammatory diseases and tumor, International Immunopharmacology, 67, 2019. Crossref

  80. Berger T. G., Schultz E. S., Dendritic Cell-Based Immunotherapy, in Dendritic Cells and Virus Infection, 276, 2003. Crossref

  81. Ferreira Isabel, Silva Ana, Martins João Demétrio, Neves Bruno Miguel, Cruz Maria Teresa, Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1, Redox Biology, 16, 2018. Crossref

  82. Rogler Gerhard, Multi-site therapeutic modalities for inflammatory bowel diseases — mechanisms of action, in Inflammatory Bowel Disease: From Bench to Bedside, 2003. Crossref

  83. Hoth J. Jason, Wells Jonathan D., Brownlee Noel A., Hiltbold Elizabeth M., Meredith J. Wayne, McCall Charles E., Yoza Barbara K., TOLL-LIKE RECEPTOR 4-DEPENDENT RESPONSES TO LUNG INJURY IN A MURINE MODEL OF PULMONARY CONTUSION, Shock, 31, 4, 2009. Crossref

  84. Wang Tiancheng, Guo Mengyao, Song Xiaojing, Zhang Zecai, Jiang Haichao, Wang Wei, Fu Yunhe, Cao Yongguo, Zhu Lianqin, Zhang Naisheng, Stevioside Plays an Anti-inflammatory Role by Regulating the NF-κB and MAPK Pathways in S. aureus-infected Mouse Mammary Glands, Inflammation, 37, 5, 2014. Crossref

  85. Hua Kuo-Feng, Chen Guan-Ming, Ho Chen-Lung, Chen Ming-Chung, Chen Yi-Lin Sophia, Chen Wei-Jung, Huang Jeng-Fang, Perng Yuan-Shing, Lin Chai-Ching, Freshwater Clam Extract Inhibits Inflammatory Responses in LPS-Activated Macrophages by Reducing the Activation of Mitogen-Activated Protein Kinases and NF-κB, Natural Product Communications, 7, 11, 2012. Crossref

  86. Oh Gi-Su, Kim Hyung-Jin, Choi Jae-Hyuck, Shen AiHua, Kim Chang-Hoi, Kim Se-Jin, Shin Sae-Ron, Hong Seung-Heon, Kim Yunha, Park Channy, Lee Sung-Joong, Akira Shizuo, Park Raekil, So Hong-Seob, Activation of Lipopolysaccharide–TLR4 Signaling Accelerates the Ototoxic Potential of Cisplatin in Mice, The Journal of Immunology, 186, 2, 2011. Crossref

  87. S. Ehlers, Hölscher C., Immunologie der Infektabwehr, in Die Infektiologie, 2004. Crossref

  88. Müller Werner, Immunologie und die Entsorgung großer Abfallprodukte, in Tier- und Humanphysiologie, 2004. Crossref

  89. Curry Jonathan L., Reuben Alexandre, Szczepaniak‐Sloane Robert, Ning Jing, Milton Denái R., Lee Chi H., Hudgens Courtney, George Saira, Torres‐Cabala Carlos, Johnson Daniel, Subramanya Sandesh, Wargo Jennifer A., Mudaliar Kumaran, Wistuba Ignacio I., Prieto Victor G., Diab Adi, Tetzlaff Michael T., Gene expression profiling of lichenoid dermatitis immune‐related adverse event from immune checkpoint inhibitors reveals increased CD14+and CD16+monocytes driving an innate immune response, Journal of Cutaneous Pathology, 46, 9, 2019. Crossref

  90. Schilling Joel D., Machkovech Heather M., He Li, Diwan Abhinav, Schaffer Jean E., TLR4 Activation Under Lipotoxic Conditions Leads to Synergistic Macrophage Cell Death through a TRIF-Dependent Pathway, The Journal of Immunology, 190, 3, 2013. Crossref

  91. Kis-Toth Katalin, Szanto Attila, Thai To-Ha, Tsokos George C., Cytosolic DNA-Activated Human Dendritic Cells Are Potent Activators of the Adaptive Immune Response, The Journal of Immunology, 187, 3, 2011. Crossref

  92. Rogler Gerhard, Multi-site therapeutic modalities for inflammatory bowel diseases — mechanisms of action, in Inflammatory Bowel Disease: From Bench to Bedside, 2005. Crossref

  93. SOMECH RAZ, AMARIGLIO NINETTE, SPIRER ZVI, RECHAVI GIDEON, Genetic predisposition to infectious pathogens: a review of less familiar variants, Pediatric Infectious Disease Journal, 22, 5, 2003. Crossref

  94. Dai Yalei, Datta Shyamsree, Novotny Michael, Hamilton Thomas A., TGFβ inhibits LPS-induced chemokine mRNA stabilization, Blood, 102, 4, 2003. Crossref

  95. Bland David A., Barrera Carlos A., Reyes Victor E., Gastrointestinal Mucosal Immunology, in Mucosal Immunology and Virology, 2006. Crossref

  96. Maitra Urmila, Gan Lu, Chang Samantha, Li Liwu, Low-Dose Endotoxin Induces Inflammation by Selectively Removing Nuclear Receptors and Activating CCAAT/Enhancer-Binding Protein δ, The Journal of Immunology, 186, 7, 2011. Crossref

  97. Fukushima Ryuichiro, Soejima Hirofumi, Fukunaga Takashi, Nakayama Masafumi, Oe Yoko, Oshima Shuichi, Sugiyama Seigo, Ogawa Hisao, Expression Levels of Toll-Like Receptor Genes in Coronary Atherosclerotic Lesions of Patients With Acute Coronary Syndrome or Stable Angina Pectoris, Circulation Journal, 73, 8, 2009. Crossref

  98. Yoshikai Yasunobu, Roles of prostaglandins and leukotrienes in acute inflammation caused by bacterial infection, Current Opinion in Infectious Diseases, 14, 3, 2001. Crossref

  99. Steckelings U. Muscha, Sumners Colin, Correcting the imbalanced protective RAS in COVID-19 with angiotensin AT2-receptor agonists, Clinical Science, 134, 22, 2020. Crossref

  100. Zhang Wei, An Eun-Koung, Hwang Juyoung, Jin Jun-O, Mice Plasmacytoid Dendritic Cells Were Activated by Lipopolysaccharides Through Toll-Like Receptor 4/Myeloid Differentiation Factor 2, Frontiers in Immunology, 12, 2021. Crossref

  101. Ishiguro Kazuhiro, Kadomatsu Kenji, Kojima Tetsuhito, Muramatsu Hisako, Iwase Mitsunori, Yoshikai Yasunobu, Yanada Masamitsu, Yamamoto Koji, Matsushita Tadashi, Nishimura Masahiko, Kusugami Kazuo, Saito Hidehiko, Muramatsu Takashi, Syndecan-4 Deficiency Leads to High Mortality of Lipopolysaccharide-injected Mice, Journal of Biological Chemistry, 276, 50, 2001. Crossref

  102. Ikwegbue Paul Chukwudi, Revaprasadu Neerish, Kappo Abidemi Paul, Therapeutic Potential of Heat Shock Proteins in Human Inflammation/Autoimmune Skin Diseases: Future Directions, in Heat Shock Proteins in Inflammatory Diseases, 22, 2020. Crossref

  103. Kirk Sean G., Murphy Parker R., Wang Xiantao, Cash Charles J., Barley Timothy J., Bowman Bridget A., Batty Abel J., Ackerman William E., Zhang Jian, Nelin Leif D., Hafner Markus, Liu Yusen, Knockout of MAPK Phosphatase-1 Exaggerates Type I IFN Response during Systemic Escherichia coli Infection, The Journal of Immunology, 206, 12, 2021. Crossref

  104. Phulphagar Kshiti, Kühn Lars I., Ebner Stefan, Frauenstein Annika, Swietlik Jonathan J., Rieckmann Jan, Meissner Felix, Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis, Cell Reports, 34, 10, 2021. Crossref

  105. Curry Jonathan L., Qin Jian-Zhong, Bonish Brian, Carrick Ryan, Bacon Patricia, Panella Jeffrey, Robinson June, Nickoloff Brian J., Innate Immune-Related Receptors in Normal and Psoriatic Skin, Archives of Pathology & Laboratory Medicine, 127, 2, 2003. Crossref

  106. Sing Andreas, Tvardovskaia Natalia, Rost Dagmar, Kirschning Carsten J., Wagner Hermann, Heesemann Jürgen, Contribution of Toll-like receptors 2 and 4 in an oral Yersinia enterocolitica mouse infection model, International Journal of Medical Microbiology, 293, 5, 2003. Crossref

  107. Sheu Fuu, Chien Po-Jung, Hsieh Kuang-Yang, Chin Kah-Lock, Huang Wan-Ting, Tsao Chiao-Yin, Chen Yin-Fang, Cheng Hui-Chung, Chang Hui-Hsin, Purification, Cloning, and Functional Characterization of a Novel Immunomodulatory Protein from Antrodia camphorata (Bitter Mushroom) That Exhibits TLR2-Dependent NF-κB Activation and M1 Polarization within Murine Macrophages, Journal of Agricultural and Food Chemistry, 57, 10, 2009. Crossref

  108. Su Kang-Yi, Yu Chao Yuan, Chen Ya-Ping, Hua Kuo-Feng, Chen Yi-Lin Sophia, 3,4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling, BMC Complementary and Alternative Medicine, 14, 1, 2014. Crossref

  109. Berman Reena, Rose Cecile S., Downey Gregory P., Day Brian J., Chu Hong Wei, Role of Particulate Matter from Afghanistan and Iraq in Deployment-Related Lung Disease, Chemical Research in Toxicology, 34, 12, 2021. Crossref

  110. Olona Antoni, Hateley Charlotte, Muralidharan Sneha, Wenk Markus R., Torta Federico, Behmoaras Jacques, Sphingolipid metabolism during Toll‐like receptor 4 (TLR4)‐mediated macrophage activation, British Journal of Pharmacology, 178, 23, 2021. Crossref

  111. Pieters Jean, Manipulation of the Macrophage Response by Pathogenic Mycobacteria, in Handbook of Tuberculosis, 2008. Crossref

  112. Yamada Kelsey J., Barker Tolga, Dyer Kimberly D., Rice Tyler A., Percopo Caroline M., Garcia-Crespo Katia E., Cho Soochin, Lee James J., Druey Kirk M., Rosenberg Helene F., Eosinophil-associated Ribonuclease 11 Is a Macrophage Chemoattractant, Journal of Biological Chemistry, 290, 14, 2015. Crossref

  113. Hise A G, Hazlett F E, Bockarie M J, Zimmerman P A, Tisch D J, Kazura J W, Polymorphisms of innate immunity genes and susceptibility to lymphatic filariasis, Genes & Immunity, 4, 7, 2003. Crossref

  114. Schilling Joel D., Machkovech Heather M., He Li, Sidhu Rohini, Fujiwara Hideji, Weber Kassandra, Ory Daniel S., Schaffer Jean E., Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages, Journal of Biological Chemistry, 288, 5, 2013. Crossref

  115. Bhatt Kamlesh, Salgame Padmini, Host Innate Immune Response to Mycobacterium tuberculosis , Journal of Clinical Immunology, 27, 4, 2007. Crossref

  116. Cao Shanjin, Zhang Xia, Edwards Justin P., Mosser David M., NF-κB1 (p50) Homodimers Differentially Regulate Pro- and Anti-inflammatory Cytokines in Macrophages, Journal of Biological Chemistry, 281, 36, 2006. Crossref

  117. Mohty M, Gaugler B, Dendritic cells: interfaces with immunobiology and medicine. A report from the Keystone Symposia Meeting held in Keystone, 3–8 March 2003, Leukemia, 17, 9, 2003. Crossref

  118. Schilling Joel D., Martin Steven M., Hung Chia S., Lorenz Robin G., Hultgren Scott J., Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli , Proceedings of the National Academy of Sciences, 100, 7, 2003. Crossref

  119. Tsolaki Anthony G., Varghese Praveen Mathews, Kishore Uday, Innate Immune Pattern Recognition Receptors of Mycobacterium tuberculosis: Nature and Consequences for Pathogenesis of Tuberculosis, in Microbial Pathogenesis, 1313, 2021. Crossref

  120. Sugawara Shunji, Interleukin-18 and oral mucosal immunity, International Congress Series, 1284, 2005. Crossref

  121. Aloisi Francesca, Immune function of microglia, Glia, 36, 2, 2001. Crossref

  122. Almeida Igor C., Gazzinelli Ricardo T., Proinflammatory activity of glycosylphosphatidylinositol anchors derived from Trypanosoma cruzi : structural and functional analyses , Journal of Leukocyte Biology, 70, 4, 2001. Crossref

  123. Berner Jakob, Weiss Tamara, Sorger Helena, Rifatbegovic Fikret, Kauer Max, Windhager Reinhard, Dohnal Alexander, Ambros Peter F., Ambros Inge M., Boztug Kaan, Steinberger Peter, Taschner‐Mandl Sabine, Human repair‐related Schwann cells adopt functions of antigen‐presenting cells in vitro, Glia, 70, 12, 2022. Crossref

  124. GHODE GAJANAN, RATHORE GAURAV, TRIPATHI GAYATRI, DAVANE KASHMIRA, PRASAD KURUCHETI PANI, Molecular cloning, characterization and constitutive expression analysis of TLR4 gene in Pangasianodon hypophthalmus, The Indian Journal of Animal Sciences, 92, 10, 2022. Crossref

  125. Paterson Hugh M., Murphy Thomas J., Purcell Elizabeth J., Shelley Odhran, Kriynovich Sara J., Lien Egil, Mannick John A., Lederer James A., Injury Primes the Innate Immune System for Enhanced Toll-Like Receptor Reactivity, The Journal of Immunology, 171, 3, 2003. Crossref

  126. Jang Sihyug, Uematsu Satoshi, Akira Shizuo, Salgame Padmini, IL-6 and IL-10 Induction from Dendritic Cells in Response to Mycobacterium tuberculosis Is Predominantly Dependent on TLR2-Mediated Recognition, The Journal of Immunology, 173, 5, 2004. Crossref

Статьи, принятые к публикации

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции Цены и условия подписки Begell House Контакты Language English 中文 Русский Português German French Spain