Library Subscription: Guest
ICHMT DL Home Current Year Archives Executive Committee International Centre for Heat and Mass Transfer

LASER INDUCED HYPERTHERMIA OF SUPERFICIAL TUMORS: A TRANSIENT THERMAL MODEL FOR INDIRECT HEATING STRATEGY

DOI: 10.1615/ICHMT.2012.CHT-12.110
pages 181-209

Victoria Timchenko
School of Mechanical and Manufacturing Engineering, The University of New South Wales, Sydney 2052, Australia

Leonid A. Dombrovsky
Joint Institute for High Temperatures, 17A Krasnokazarmennaya Str., Moscow, 111116, Russia; Tyumen State University, 6 Volodarsky Str., Tyumen, 625003, Russia

Abstract

An indirect heating strategy based on laser irradiation of surrounding tissues as an alternative to a direct irradiation of superficial tumors is presented in this paper. The computational analysis is based on two-dimensional axisymmetric models for both radiative transfer and transient heat transfer in a human body. Coupled transient energy equations and kinetic equations for composite human tissue take into account the metabolic heat generation and heat conduction, blood perfusion through capillaries, the volumetric heat transfer between arterial blood and ambient tissue, the thermal conversions in blood and tumor tissue, the periodic laser heating, and also heat transfer between the human body and ambient medium. An example problem for a superficial human cancer has been solved numerically to illustrate the relative role of the problem parameters on the transient temperature field and degree of thermal conversions in human tissues during hyperthermia treatment. In particular, the effect of embedded gold nanoshells which strongly absorb the laser radiation is analyzed. It is shown that required parameters of tumor hyperthermia can be also reached without gold nanoshells.

ICHMT Digital Library

Bow shocks on a jet-like solid body shape. Thermal Sciences 2004, 2004. Pulsed, supersonic fuel jets - their characteristics and potential for improved diesel engine injection. PULSED, SUPERSONIC FUEL JETS - THEIR CHARACTERISTICS AND POTENTIAL FOR IMPROVED DIESEL ENGINE INJECTION
View of engine compartment components (left). Plots of temperature distributions in centreplane, forward of engine (right). CHT-04 - Advances in Computational Heat Transfer III, 2004. Devel... DEVELOPMENT AND CURRENT STATUS OF INDUSTRIAL THERMOFLUIDS CFD ANALYSIS
Pratt & Whitney's F-135 Joint Strike Fighter Engine under test in Florida is a 3600F class jet engine. TURBINE-09, 2009. Turbine airfoil leading edge stagnation aerodynamics and heat transfe... TURBINE AIRFOIL LEADING EDGE STAGNATION AERODYNAMICS AND HEAT TRANSFER - A REVIEW
Refractive index reconstructed field. (a) Second iteration. (b) Fourth iteration. Radiative Transfer - VI, 2010. Theoretical development for refractive index reconstruction from a radiative ... THEORETICAL DEVELOPMENT FOR REFRACTIVE INDEX RECONSTRUCTION FROM A RADIATIVE TRANSFER EQUATION-BASED ALGORITHM
Two inclusion test, four collimated sources. Radiative Transfer - VI, 2010. New developments in frequency domain optical tomography. Part II. Application with a L-BFGS associated to an inexa... NEW DEVELOPMENTS IN FREQUENCY DOMAIN OPTICAL TOMOGRAPHY. PART II. APPLICATION WITH A L-BFGS ASSOCIATED TO AN INEXACT LINE SEARCH