RT Journal Article ID 5d0eb34878582d1d A1 Ruley, H. Earl A1 Rubin, Donald H. T1 Cellular Genetics of Host Susceptibility and Resistance to Virus Infection JF Critical Reviews™ in Eukaryotic Gene Expression JO CRE YR 2006 FD 2006-05-25 VO 16 IS 2 SP 155 OP 170 AB Viruses are obligate intracellular parasites that rely upon the host cell for activities essential to their life cycles. Gene-trap mutagenesis provides a rapid, genome-wide strategy to identify candidate cellular genes required for virus replication. The candidate genes provide a starting point for mechanistic studies of cellular processes that participate in the virus life cycle and may provide targets for novel antiviral therapies. PB Begell House LK https://www.dl.begellhouse.com/journals/6dbf508d3b17c437,2d39b24c5067c643,5d0eb34878582d1d.html