RT Journal Article
ID 3b73a6430bf83bed
A1 Kashina, Svetlana
A1 Villavicencio, Lerida Liss Flores
A1 Zaina, Silvio
A1 Ordaz, Marco Balleza
A1 Sabanero, Gloria Barbosa
A1 Fujiyoshi, Victor Tsutsumi
A1 Lopez, Myrna Sabanero
T1 Activity of Extracts from Submerged Cultured Mycelium of Winter Mushroom, Flammulina velutipes (Agaricomycetes), on the Immune System In Vitro
JF International Journal of Medicinal Mushrooms
JO IJM
YR 2016
FD 2016-03-09
VO 18
IS 1
SP 49
OP 57
K1 medicinal mushrooms
K1 Flammulina velutipes
K1 monocytes
K1 macrophages
K1 glycans
AB Extracts from submerged cultured mycelium of two strains of Flammulina velutipes, a popular culinary mushroom, were obtained by ultrasound and tested in vitro to determine their activity in innate immunity (monocytes/
macrophages). In addition, polyclonal antibodies against the extracts were produced. Both extracts have similar glycoproteins that contain mannose and glucose but have different glycoproteins with galactoseamine units. Two novel
immunogenic glycoproteins with molecular weights of 32 and 25 kDa have been revealed. It is thought that these
proteins are produced only by submerged cultured mycelium. Both extracts show immune-enhancing activity based
on the significant modification of various parameters such as cytokine production, phagocytosis, and reactive oxygen
species production.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,33df00905b660ea5,3b73a6430bf83bed.html