RT Journal Article ID 033c7f5d13565c4f A1 Tang, Xiaoqing A1 Cai, Weixi A1 Xu, Baojun (Bruce) T1 Comparison of the Chemical Profiles and Antioxidant and Antidiabetic Activities of Extracts from Two Ganoderma Species (Agaricomycetes) JF International Journal of Medicinal Mushrooms JO IJM YR 2016 FD 2016-09-12 VO 18 IS 7 SP 609 OP 620 K1 α-glycosidase K1 antioxidants K1 ganoderic acids K1 Ganoderma lucidum K1 Ganoderma sinense K1 medicinal mushrooms AB The objective of this study was to compare the mycochemical profiles, antioxidant activities, and antidiabetic effects of 2 species of genus Ganoderma, the red lingzhi (G. lucidum) and purple lingzhi (G. sinense) mushrooms. In Chinese medicinal practice, hot water and ethanol are used as solvents to extract samples. In this study, a total of 4 extracts (ethanol and hot water extracts from G. lucidum and G. sinense) were prepared for further assays. Hot water extracts presented much higher values for total phenolic content and ferric-reducing antioxidant power than the ethanol extracts. Ethanol (70%) extract of G. lucidum had the strongest α-glycosidase inhibitory capacity, but the lingzhi polysaccharides showed no inhibitory effect. It also had the largest amount of total ganoderic acids. The results indicated that ethanol extracts from both G. lucidum and G. sinense showed better antidiabetic effects than the hot water extracts. Ganoderic acids, rather than polysaccharides, may contribute the antidiabetic effects of both the Ganoderma species. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,65a55c177b27d486,033c7f5d13565c4f.html