Publicou 12 edições por ano
ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344
Indexed in
Effect of Culture Conditions on the Chemical Composition and Biological Activities of Agaricus brasiliensis S.Wasser et al. (Agaricomycetideae)
RESUMO
Agaricus brasiliensis is included in many kinds of health foods. Both the fruit body and mycelium, cultured in various countries from various strains and using various production processes, are supplied. In the present study, we planned to compare the chemical properties and biological activities of A. brasiliensis cultured under different conditions, i.e., indoors in a house (IC) and outside on a field (OC), using the same strain and the same production process. Polysaccharide fractions prepared from IC and OC had similar structural features and biological activity, as assessed by component sugar analysis, nuclear magnetic resonance, and antitumor activity in vivo. In contrast, the protein fractions were qualitatively different, i.e., specific protein spots were detected by two-dimensional polyacrylamide gel electrophoresis, and the enzyme activities, especially laccase, polyphenoloxidase, peroxidase, and beta-glucanase activities, were different. These facts strongly suggested that the culture conditions of medicinal mushrooms are keys for their pharmacological activity assessment.
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Yamanaka Daisuke, Motoi Masuro, Ishibashi Ken-ichi, Miura Noriko N., Adachi Yoshiyuki, Ohno Naohito, Effect ofAgaricus brasiliensis-derived cold water extract on Toll-like receptor 2-dependent cytokine productionin vitro, Immunopharmacology and Immunotoxicology, 34, 4, 2012. Crossref
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Yamanaka Daisuke, Tada Rui, Adachi Yoshiyuki, Ishibashi Ken-ichi, Motoi Masuro, Iwakura Yoichiro, Ohno Naohito, Agaricus brasiliensis-derived β-glucans exert immunoenhancing effects via a dectin-1-dependent pathway, International Immunopharmacology, 14, 3, 2012. Crossref
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Yamanaka Daisuke, Tamiya Yumi, Motoi Masuro, Ishibashi Ken-ichi, Miura Noriko N., Adachi Yoshiyuki, Ohno Naohito, Heimesaat Markus M., The Effect of Enzymatically Polymerised Polyphenols on CD4 Binding and Cytokine Production in Murine Splenocytes, PLoS ONE, 7, 4, 2012. Crossref
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Hamuro Yuhi, Tajima Katsuya, Matsumoto-Akanuma Akiko, Sakamoto Sayaka, Furukawa Ryutaro, Yamagishi Akihiko, Ohno Naohito, Akanuma Satoshi, Characterization of a thermostable mutant of Agaricus brasiliensis laccase created by phylogeny-based design, Journal of Bioscience and Bioengineering, 124, 6, 2017. Crossref
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Camelini Carla Maísa, Rossi M. J., Cardozo F. T. G. S., Gomes A., Sales-Campos C., Giachini A. J., Fungal Cultivation and Production of Polysaccharides, in Polysaccharides, 2014. Crossref
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Niwa Atsuko, Tajiri Takashi, Higashino Hideaki, Ipomoea batatas and Agarics blazei ameliorate diabetic disorders with therapeutic antioxidant potential in streptozotocin-induced diabetic rats, Journal of Clinical Biochemistry and Nutrition, 48, 3, 2011. Crossref
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Camelini Carla Maísa, Rossi Márcio José, Cardozo Francielle T. G. S., Gomes A., Sales-Campos Ceci, Giachini Admir J., Fungal Cultivation and Production of Polysaccharides, in Polysaccharides, 2015. Crossref
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Yamanaka Daisuke, Motoi Masuro, Motoi Akitomo, Ohno Naohito, Differences in antioxidant activities of outdoor- and indoor-cultivated Agaricus brasiliensis, and protective effects against carbon tetrachloride-induced acute hepatic injury in mice, BMC Complementary and Alternative Medicine, 14, 1, 2014. Crossref