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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Investigation of Antiproliferative Effect of Ether and Ethanol Extracts of Birch Polypore Medicinal Mushroom, Piptoporus betulinus (Bull.:Fr.) P. Karst. (Higher Basidiomycetes) In Vitro Grown Mycelium

Volume 13, Edição 6, 2011, pp. 525-533
DOI: 10.1615/IntJMedMushr.v13.i6.40
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RESUMO

This paper describes the study conducted to evaluate the antiproliferative activity of ether and ethanol extracts isolated from Piptoporus betulinus against cancer-derived cells. The fungal material used for extract preparation and further experiments was obtained from in vitro grown strains of P. betulinus. To the best of the authors’ knowledge, this is the first study evaluating antiproliferative potential of in vitro cultured birch polypore fungus. The effect of ether and ethanol extracts on cell proliferation, viability, and adhesion was assessed on colorectal adenocarcinoma cancer cell line LS180, whereas the cytotoxicity effect was investigated in normal colon epithelium-derived cell line CCD 841 CoTr. Studied extracts highly decreased the viability of cancer cells, slightly inhibiting proliferation and tumor cell adhesion in a time- and dose-dependent manner. Cytotoxicity of extracts against cells of normal colon epithelium origin was observed only at the highest studied concentration. The obtained results may seem interesting in comparison with previous studies on water extracts from natural grown P. betulinus. Future research on mycelial extract activity, as well as the content analysis, is needed.

CITADO POR
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  2. Papp Nóra, Rudolf Kinga, Bencsik Tímea, Czégényi Dóra, Ethnomycological use of Fomes fomentarius (L.) Fr. and Piptoporus betulinus (Bull.) P. Karst. in Transylvania, Romania, Genetic Resources and Crop Evolution, 64, 1, 2017. Crossref

  3. Pleszczyńska Małgorzata, Wiater Adrian, Siwulski Marek, Lemieszek Marta K., Kunaszewska Justyna, Kaczor Józef, Rzeski Wojciech, Janusz Grzegorz, Szczodrak Janusz, Cultivation and utility of Piptoporus betulinus fruiting bodies as a source of anticancer agents, World Journal of Microbiology and Biotechnology, 32, 9, 2016. Crossref

  4. Doskocil Ivo, Havlik Jaroslav, Verlotta Roberta, Tauchen Jan, Vesela Lucia, Macakova Katerina, Opletal Lubomir, Kokoska Ladislav, Rada Vojtech, In vitroimmunomodulatory activity, cytotoxicity and chemistry of some central European polypores, Pharmaceutical Biology, 54, 11, 2016. Crossref

  5. Pleszczyńska Małgorzata, Lemieszek Marta K., Siwulski Marek, Wiater Adrian, Rzeski Wojciech, Szczodrak Janusz, Fomitopsis betulina (formerly Piptoporus betulinus): the Iceman’s polypore fungus with modern biotechnological potential, World Journal of Microbiology and Biotechnology, 33, 5, 2017. Crossref

  6. Tohtahon Zeynep, Xue Jingjing, Han Jianxin, Liu Yushuang, Hua Huiming, Yuan Tao, Cytotoxic lanostane triterpenoids from the fruiting bodies of Piptoporus betulinus, Phytochemistry, 143, 2017. Crossref

  7. Sułkowska-Ziaja Katarzyna, Szewczyk Agnieszka, Galanty Agnieszka, Gdula-Argasińska Joanna, Muszyńska Bożena, Chemical composition and biological activity of extracts from fruiting bodies and mycelial cultures of Fomitopsis betulina, Molecular Biology Reports, 45, 6, 2018. Crossref

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  10. Bożek Justyna, Tomala Joanna, Wójcik Sylwia, Kamińska Beata, Brand Izabella, Pocheć Ewa, Szostak Elżbieta, Effects of Piptoporus betulinus Ethanolic Extract on the Proliferation and Viability of Melanoma Cells and Models of Their Cell Membranes, International Journal of Molecular Sciences, 23, 22, 2022. Crossref

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