Inscrição na biblioteca: Guest
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa
International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volumes:
Volume 22, 2020 Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v5.i1.20
8 pages

Production of Polysaccharide by Culinary-Medicinal Mushroom Agaricus brasiliensis S. Wasser et al. LPB 03 (Agaricomycetideae) in Submerged Fermentation and Its Antitumor Effect

Leifa Fan
Laboratorio de Processos Biotecnologicos, Departamento de Engenharia Quimica, Universidade Federal do Parana. Centro Politecnico, Curitiba PR, CEP: 81531-990, Brazil
Andrea Thomaz Soccol
Laboratorio de Processos Biotecnologicos, Departamento de Engenharia Quimica, Universidade Federal do Parana. Centro Politecnico, Curitiba PR, CEP: 81531-990, Brazil
Ashok Pandey
Biotechnology Division, Regional Research Laboratory, CSIR, Trivandrum-695 019, India; and 3Instituto de Tecnologia do Parana, TECPAR, CIC, Curitiba PR, CEP: 81350-010, Brazil
Sandro Germano
Laboratorio de Processos Biotecnologicos, Departamento de Engenharia Quimica, Universidade Federal do Parana. Centro Politecnico, Curitiba PR, CEP: 81531-990, Brazil
Renato Rau
Instituto de Tecnologia do Parana, TECPAR, CIC, Curitiba PR, CEP: 81350-010, Brazil
Aurora L. Pedroso
Instituto de Tecnologia do Parana, TECPAR, CIC, Curitiba PR, CEP: 81350-010, Brazil
Carlos Ricardo Soccol
Bioprocess Engineering and Biotechnology Division, Federal University of Paraná, Curitiba, Paraná, Brazil

RESUMO

Studies were performed on the production of extracellular polysaccharide in submerged culture of Agaricus brasiliensis Wasser et al. and the effects of different carbon and nitrogen sources individually and in combinations on production. The polysaccharide produced was evaluated for its antitumor action against Sarcoma 180. Glucose and yeast extract gave the best combination of carbon and nitrogen sources for the polysaccharide production. The biomass yield and polysaccharide produced were 222.3 and 10.867 mg/50 mL (dry wt), respectively, at the concentration of 20 g/L glucose and 2 g/L yeast extract with the medium containing MgSO4Ч7H2O (0.1%) and K2HPO4Ч3H2O (0.1%) at pH 6.0 and 32°C after the 9 days' static cultivation. The extracellular polysaccharide showed strong antitumor activity against Sarcoma 180. Complete regression ratio of 50% and suppression ratio percentage of 72.19% were observed.


Articles with similar content:

Optimization of Submerged Cultivation Conditions for Extra- and Intracellular Polysaccharide Production by Medicinal Ling Zhi or Reishi Mushroom Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae)
International Journal of Medicinal Mushrooms, Vol.10, 2008, issue 4
Jasmina Simonic, Jelena Vukojević, Ilija Brceski, Sonja Duletic-Lausevic, Mirjana Stajic, Jasmina Glamoclija
Optimization of Submerged Fermentation Conditions for Lovastatin Production by the Culinary-Medicinal Oyster Mushroom, Pleurotus ostreatus (Higher Basidiomycetes)
International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 5
Zeki Yildiz, Mustafa Yamac, Burcu Atli
Production of Ligninolytic Enzymes by Oyster Mushroom Pleurotus ostreatus (Jacq.:Fr.) P. Kumm. Under Different Nutritional Conditions
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Nona A. Mikiashvili
Submerged and Solid-State Cultivation of Bioactive Extra- and Intracellular Polysaccharides of Medicinal Mushrooms Ganoderma lucidum (W. Curt.: Fr.) P. Karst. and Grifola frondosa (Dicks.: Fr.) S. F. Gray (Aphyllophoromycetideae)
International Journal of Medicinal Mushrooms, Vol.11, 2009, issue 4
Branka Wraber, Jozica Habijanic, Mirjan Svagelj, Bojana Boh, Marin BEROVIC
Isolation and Characterization of Lectin from the Artist's Conk Medicinal Mushroom, Ganoderma applanatum (Agaricomycetes), and Evaluation of Its Antiproliferative Activity in HT-29 Colon Cancer Cells
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 8
Ashok Kumar Pandurangan, Norhaizan Mohd. Esa, Sekar Kumaran, Ramalingam Shenbhagaraman