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International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volumes:
Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v1.i4.50
pages 331-336

The Action of Higher Basidiomycetes Mushrooms Mycelia on Plasma Lipids and Lipoproteins of Hyperlipidemic Rats and Guinea Pigs

Olga V. Remesova
Department of Biochemistry, Institute of Experimental Medicine, Russian Academy of Medical Sciences, 12 Ac. Pavlov Str., Saint Petersburg 197376, Russia
Nina P. Denisova
V. L. Komarov Botanical Institute Russian Academy of Sciences Prof. Popova Str. 2 St. Petersburg 197376, Russia

RESUMO

Experiments in rats and guinea pigs have shown that mycelia of two mushrooms, Flammulina velutipes (Curt.: Fr.) P.Karst., and Coprinus domesticus (Bolt.: Fr.) S.F. Gray, reduced contents of total cholesterol in the blood serum and liver under conditions of induced hyperlipidemia. High levels of triglycerides in guinea pigs were decreased by administering the studied mycelia. The cholesterol index of atherogenicity and liver index declined significantly. Moreover, it was documented that the mycelia of the two mushrooms improved lipoprotein metabolism by decreasing the content of low-density lipoproteins and increasing the content of high-density lipoproteins. The data support recommendations to use F. velutipes and C. domesticus mycelia for prevention and treatment of atherosclerosis.


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