Publicou 12 edições por ano
ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344
Indexed in
Did the Iceman Know Better? Screening of the Medicinal Properties of the Birch Polypore Medicinal Mushroom, Piptoporus betulinus (Higher Basidiomycetes)
RESUMO
The birch polypore Piptoporus betulinus was among two mushrooms that were found in the Iceman's bag. Recent studies indicated that P. betulinus was probably used as a religious and medicinal item. In order to examine the medicinal potential of P. betulinus, hot water (HW), partially purified (PP), and alkali extract (HA) were prepared and tested for antioxidant, antimicrobial, cytotoxic, and angiotensin I−converting enzyme (ACE) inhibitory activity. All tested samples exhibited moderate cytotoxic activity, and HW appeared as the most effective (IC50 = 0.8 ± 0.1 mg/ml for HeLa cells). HA proved to be a good 1,1-diphenyl-2-picrylhydrazyl radical scavenger and exhibited the strongest ferric-reducing power (EC50 = 0.07 ± 0.3 mg/ml). The same extract (HA) also expressed the strongest ferric-reducing power (EC50 = 0.99 ± 0.1 mg/ml). Hot alkali extraction contributed significantly to ACE inhibitory activity (EC50 = 0.06 ± 0.00 mg/ml) and to antimicrobial activity, especially against highly resistant Enterococcus faecalis (minimum inhibitory concentration: 0.156 ± 0.000 mg/ml; and minimum bactericidal concentration: 1.25 ± 0.00 mg/ml).
-
Kozarski Maja, Klaus Anita, Jakovljevic Dragica, Todorovic Nina, Vunduk Jovana, Petrović Predrag, Niksic Miomir, Vrvic Miroslav, van Griensven Leo, Antioxidants of Edible Mushrooms, Molecules, 20, 10, 2015. Crossref
-
Pleszczyńska Małgorzata, Lemieszek Marta K., Siwulski Marek, Wiater Adrian, Rzeski Wojciech, Szczodrak Janusz, Fomitopsis betulina (formerly Piptoporus betulinus): the Iceman’s polypore fungus with modern biotechnological potential, World Journal of Microbiology and Biotechnology, 33, 5, 2017. Crossref
-
Singh Deeptej, Fisher Juliya, Shagalov Devorah, Varma Aakaash, Siegel Daniel M., Dangerous plants in dermatology: Legal and controlled, Clinics in Dermatology, 36, 3, 2018. Crossref
-
Phan Chia-Wei, Tan Elson Yi-Yong, Sabaratnam Vikineswary, Bioactive Molecules in Edible and Medicinal Mushrooms for Human Wellness, in Sweeteners, 2018. Crossref
-
Phan Chia-Wei, Tan Elson Yi-Yong, Sabaratnam Vikineswary, Bioactive Molecules in Edible and Medicinal Mushrooms for Human Wellness, in Bioactive Molecules in Food, 2019. Crossref
-
Gründemann Carsten, Reinhardt Jakob K., Lindequist Ulrike, European medicinal mushrooms: Do they have potential for modern medicine? – An update, Phytomedicine, 66, 2020. Crossref
-
Krupodorova Tetiana, Barshteyn Victor, Pokas Elena, ANTIBACTERIAL ACTIVITY OF FOMITOPSIS BETULINA CULTURAL LIQUID, EUREKA: Life Sciences, 6, 2019. Crossref
-
Novakovic S, Djekic I, Vunduk J, Klaus A, Lorenzo JM, Barba F, Tomasevic I, An insight into in vitro antioxidant activity of Cantharellus cibarius hot water extract for the potential application in meat products, IOP Conference Series: Earth and Environmental Science, 333, 1, 2019. Crossref
-
de Jesus Liana Inara, Smiderle Fhernanda R., Cordeiro Lucimara M.C., de Freitas Rilton A., Van Griensven Leo J.L.D., Iacomini Marcello, Simple and effective purification approach to dissociate mixed water-insoluble α- and β-D-glucans and its application on the medicinal mushroom Fomitopsis betulina, Carbohydrate Polymers, 200, 2018. Crossref
-
Chun Sechul, Gopal Judy, Muthu Manikandan, Antioxidant Activity of Mushroom Extracts/Polysaccharides—Their Antiviral Properties and Plausible AntiCOVID-19 Properties, Antioxidants, 10, 12, 2021. Crossref
-
de Jesus Liana Inara, Smiderle Fhernanda R., Ruthes Andrea C., Vilaplana Francisco, Dal'Lin Fernando Tonholi, Maria-Ferreira Daniele, Werner Maria Fernanda, Van Griensven Leo J.L.D., Iacomini Marcello, Chemical characterization and wound healing property of a β-D-glucan from edible mushroom Piptoporus betulinus, International Journal of Biological Macromolecules, 117, 2018. Crossref