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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Influence of Storage Conditions on Immunomodulating Activities in Lentinus edodes (Berk.)Sing. (Agaricales s.l., Basidiomycetes)

Volume 1, Edição 3, 1999, pp. 243-250
DOI: 10.1615/IntJMedMushrooms.v1.i3.70
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RESUMO

The immunomodulating activities of tumor necrosis factor-α (TNF-α) and nitric oxide (NO) production from mouse macrophages stimulated with extract from Lentinus edodes (Berk.)Sing. stored under different conditions were investigated. TNF-α production was approximately 60 pg ml−1 from macrophages stimulated with the extract from fresh L. edodes in vitro. This effect of the extract from the stored L. edodes showed no drastic difference under low temperature (1 and 5°C) storage. However, TNF-α production from macrophages stimulated with extract from L. edodes stored at 20°C for 7 days decreased to approximately 12 pg ml−1. Also, TNF-α production in vivo from macrophages stimulated with the extract from L. edodes stored at 20°C decreased approximately 20%, compared with that made from the fresh mushroom. This result showed the same tendency as in vitro. NO production from macrophages stimulated with the fresh mushroom extract was 7.4 μM. Although NO production from macrophages stimulated with the extract from the mushroom stored at low temperature was not different significantly from that observed in the fresh L. edodes extract, its production was scarcely detected in the extract from L. edodes stored at 20°C for 7 days. Moreover, lentinan was enzymatically degraded by β-glucanase in L. edodes; in addition the effect of lentinan on the production of these cytokines was decreased with degradation of lentinan. These results showed that the decrease of immunomodulating activities in L. edodes might be reflected by the reduction of lentinan content, which was degraded by β-glucanase during storage of the mushroom.

CITADO POR
  1. Okamoto Takashi, Kodoi Rie, Nonaka Yuji, Fukuda Itsuko, Hashimoto Takashi, Kanazawa Kazuki, Mizuno Masashi, Ashida Hitoshi, Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver, BioFactors, 21, 1-4, 2004. Crossref

  2. Zhang Yangyang, Xu Xiaojuan, Zhang Lina, Gel formation and low-temperature intramolecular conformation transition of a triple-helical polysaccharide lentinan in water, Biopolymers, 89, 10, 2008. Crossref

  3. DE LIMA PATRICIA L. ALVES, RIBEIRO DANIEL A, SUGUI MARINA M, TEREZAN ANA PAULA, DOMINGUES MARIA APARECIDA C, FILHO E R, AZEVEDO LUCIANA, SALVADORI DAISY M F, RIBEIRO LUCIA R, STORAGE RESULTS IN LOSS OF THE ANTIGENOTOXIC PROPERTIES OFLENTINULA EDODES(SHIITAKE MUSHROOM) AND DEVELOPMENT OFIN VIVOGENOTOXICITY, Journal of Food Biochemistry, 34, 1, 2010. Crossref

  4. Pacheco-Sánchez Maribel, Boutin Yvan, Angers Paul, Gosselin André, Tweddell Russell J., Inhibitory effect of CDP, a polysaccharide extracted from the mushroom Collybia dryophila, on nitric oxide synthase expression and nitric oxide production in macrophages, European Journal of Pharmacology, 555, 1, 2007. Crossref

  5. Zhang Yangyang, Li Sheng, Wang Xiaohua, Zhang Lina, Cheung Peter C.K., Advances in lentinan: Isolation, structure, chain conformation and bioactivities, Food Hydrocolloids, 25, 2, 2011. Crossref

  6. Finimundy T.C., Gambato G., Fontana R., Camassola M., Salvador M., Moura S., Hess J., Henriques J.A.P., Dillon A.J.P., Roesch-Ely M., Aqueous extracts of Lentinula edodes and Pleurotus sajor-caju exhibit high antioxidant capability and promising in vitro antitumor activity, Nutrition Research, 33, 1, 2013. Crossref

  7. Wilbers Ruud H. P., Westerhof Lotte B., van de Velde Jan, Smant Geert, van Raaij Debbie R., Sonnenberg Anton S. M., Bakker Jaap, Schots Arjen, Physical Interaction of T Cells with Dendritic Cells Is Not Required for the Immunomodulatory Effects of the Edible Mushroom Agaricus subrufescens, Frontiers in Immunology, 7, 2016. Crossref

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