Publicou 12 edições por ano
ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344
Indexed in
Moderate Angiotensin I Converting Enzyme (ACE) Inhibitors from the Edible Mushroom Pleurotus citrinopileatus Singer (Agaricomycetideae)
RESUMO
The acetone extract of Pleurotus citrinopileatus showed a moderate inhibitory activity against the angiotensin I converting enzyme (ACE). The 50% inhibitory concentration (IC50) of the extract for ACE activity was 50.2 mg ml−1. D-mannitol was isolated as an active principle with a yield of 5.75 %. The IC50 value of the compound was 33.4 mg ml−1. D-arabitol and glycerol were also detected in the acetone extract. D-arabitol acted as an ACE inhibitor, whereas only limited activity was observed by the dose of glycerol.
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Kiyoto Masaaki, Saito Shingo, Hattori Kazuyuki, Cho Nam-Seok, Hara Takaaki, Yagi Yuzo, Aoyama Masakazu, Inhibitory effects of l-pipecolic acid from the edible mushroom, Sarcodon aspratus, on angiotensin I-converting enzyme, Journal of Wood Science, 54, 2, 2008. Crossref