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Critical Reviews™ in Eukaryotic Gene Expression

Publicou 6 edições por ano

ISSN Imprimir: 1045-4403

ISSN On-line: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Mammalian Cell DNA Replication

Volume 7, Edição 1-2, 1997, pp. 125-157
DOI: 10.1615/CritRevEukarGeneExpr.v7.i1-2.80
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RESUMO

The precise mechanisms involved in the regulation of the mammalian cell DNA-synthesizing machinery are poorly understood. In vitro DNA replication systems, in particular the employment of the simian virus 40 (SV40)-based cell-free DNA replication system, has identified several mammalian enzymes and proteins required for DNA synthesis. Although these proteins have been identified as playing a role in DNA replication, their functional organization allowing for the efficient replication of DNA has not been well defined.
This review describes the proteins that have currently been defined as having a role in mammalian DNA replication and their proposed mechanisms of action. How these proteins may organize themselves to form multiprotein complexes, or larger DNA replication factories, allowing for efficient chromosomal DNA synthesis is discussed. In addition, the cell cycle regulation of mammalian DNA synthesis and the current status concerning mammalian DNA replication origins is described.

CITADO POR
  1. Zannis-Hadjopoulos Maria, Price Gerald B., Eukaryotic DNA replication, Journal of Cellular Biochemistry, 75, S32, 1999. Crossref

  2. Malkas Linda H., DNA replication machinery of the mammalian cell, Journal of Cellular Biochemistry, 72, S30-31, 1998. Crossref

  3. Han Suhua, Hickey Robert J, Tom Timothy D, Wills Philip W, Syväoja Juhani E, Malkas Linda H, Differential inhibition of the human cell DNA replication complex-associated DNA polymerases by the antimetabolite 1-β-d-arabinofuranosylcytosine triphosphate (ara-CTP), Biochemical Pharmacology, 60, 3, 2000. Crossref

  4. Jenkins J R, A proteomic approach to identifying new drug targets (potentiating topoisomerase II poisons), The British Journal of Radiology, 81, special_issue_1, 2008. Crossref

  5. Goldsby Robert E., Singh Mallika, Preston Bradley D., Mouse DNA polymerase δ gene (Pold1) maps to Chromosome 7, Mammalian Genome, 9, 1, 1998. Crossref

  6. Keck James L, Berger James M, DNA replication at high resolution, Chemistry & Biology, 7, 3, 2000. Crossref

  7. Patel Premal H., Loeb Lawrence A., DNA-Dependent DNA Polymerases, in Encyclopedia of Molecular Biology, 2002. Crossref

  8. Sandoval John A., Hickey Robert J., Malkas Linda H., Isolation and characterization of a DNA synthesome from a neuroblastoma cell line, Journal of Pediatric Surgery, 40, 7, 2005. Crossref

  9. Simmons Daniel T., Trowbridge Pamela W., Roy Rupa, Topoisomerase I Stimulates SV40 T Antigen-Mediated DNA Replication and Inhibits T Antigen's Ability to Unwind DNA at Nonorigin Sites, Virology, 242, 2, 1998. Crossref

  10. Hammoud Zane T., Badve Sunil, Saxena Romil, Kesler Kenneth A., Rieger Karen, Malkas Linda H., Hickey Robert J., A novel biomarker for the detection of esophageal adenocarcinoma, The Journal of Thoracic and Cardiovascular Surgery, 133, 1, 2007. Crossref

  11. Woynarowski Jan M, Chapman William G, Napier Cheryl, Herzig Maryanne C.S, Induction of AT-specific DNA-interstrand crosslinks by bizelesin in genomic and simian virus 40 DNA, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1444, 2, 1999. Crossref

  12. Cordeiro-Stone Marila, Nikolaishvili-Feinberg Nana, Asymmetry of DNA replication and translesion synthesis of UV-induced thymine dimers, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 510, 1-2, 2002. Crossref

  13. Srivastava Pramod K, Menoret Antoine, Basu Sreyashi, Binder Robert J, McQuade Kristi L, Heat Shock Proteins Come of Age: Primitive Functions Acquire New Roles in an Adaptive World, Immunity, 8, 6, 1998. Crossref

  14. Jiang Hai Yan, Hickey Robert J., Abdel-Aziz Waleed, Tom Timothy D., Wills Philip W., Liu Jianying, Malkas Linda H., Human cell DNA replication is mediated by a discrete multiprotein complex, Journal of Cellular Biochemistry, 85, 4, 2002. Crossref

  15. Lattanzi Giovanna, Galanzi Angela, Gobbi Pietro, Falconi Mirella, Matteucci Alessandro, Breschi Lorenzo, Vitale Marco, Mazzotti Giovanni, Ultrastructural Aspects of the DNA Polymerase α Distribution During the Cell Cycle, Journal of Histochemistry & Cytochemistry, 46, 12, 1998. Crossref

  16. Krüger Ricardo, Rakowski Sheryl A., Filutowicz Marcin, Participating Elements in the Replication of Iteron-Containing Plasmids, in Plasmid Biology, 2014. Crossref

  17. Hickey Robert J, Hoelz Derek J, Malkas Linda H, DNA Replication: Mammalian, in eLS, 2003. Crossref

  18. Pommier Yves, Kohlhagen Glenda, Wu Chunxiao, Simmons Daniel T., Mammalian DNA Topoisomerase I Activity and Poisoning by Camptothecin Are Inhibited by Simian Virus 40 Large T Antigen, Biochemistry, 37, 11, 1998. Crossref

  19. Trowbridge Pamela W., Roy Rupa, Simmons Daniel T., Human Topoisomerase I Promotes Initiation of Simian Virus 40 DNA Replication In Vitro, Molecular and Cellular Biology, 19, 3, 1999. Crossref

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