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Critical Reviews™ in Eukaryotic Gene Expression
Fator do impacto: 1.841 FI de cinco anos: 1.927 SJR: 0.649 SNIP: 0.516 CiteScore™: 1.96

ISSN Imprimir: 1045-4403
ISSN On-line: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukaryotGeneExpr.2018024602
pages 205-215

Methods for Detecting Human Meiotic Recombination Hotspots

Mahmut Cerkez Ergoren
Near East University, Faculty of Medicine, Department of Medical Biology, 99138, Nicosia, Cyprus; Near East University, Research Center of Experimental Health Sciences (DESAM), 99138, Nicosia, Cyprus

RESUMO

Traditional methods for analyzing meiotic recombination in humans are limited. Recently developed in vitro and in silico assays together are useful for confirmation and detection of meiotic recombination hotspots from population polymorphism data. These techniques are significant both for understanding the nature of human meiotic recombination and for applications such as association studies.

Palavras-chave: genome, diversity, meiosis, techniques