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Critical Reviews™ in Eukaryotic Gene Expression
Fator do impacto: 2.156 FI de cinco anos: 2.255 SJR: 0.649 SNIP: 0.599 CiteScore™: 3

ISSN Imprimir: 1045-4403
ISSN On-line: 2162-6502

Volume 30, 2020 Volume 29, 2019 Volume 28, 2018 Volume 27, 2017 Volume 26, 2016 Volume 25, 2015 Volume 24, 2014 Volume 23, 2013 Volume 22, 2012 Volume 21, 2011 Volume 20, 2010 Volume 19, 2009 Volume 18, 2008 Volume 17, 2007 Volume 16, 2006 Volume 15, 2005 Volume 14, 2004 Volume 13, 2003 Volume 12, 2002 Volume 11, 2001 Volume 10, 2000 Volume 9, 1999 Volume 8, 1998 Volume 7, 1997 Volume 6, 1996 Volume 5, 1995 Volume 4, 1994

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukaryotGeneExpr.2019025864
pages 319-332

Advanced Approaches Based on Expression of Different Genes and Biomarkers for the Diagnosis and Treatment of Renal Disorders

Monika Sharma
Department of Bioscience and Biotechnology, Banasthali Vidyapith (Women's University), Rajasthan, India
Varsha Pandey
Department of Bioscience and Biotechnology, Banasthali Vidyapith (Women's University), Rajasthan, India
Chandra Kant Sharma
Institute of Agricultural Science, SAGE University, Indore, India-452020


This review focuses on the causes and complications of chronic kidney disease (CKD). The kidneys are major organs boasting various natural functions, chief among them the stable equilibrium of body fluids by eliminating waste. If the symptoms of CKD can be detected early, effective care is possible. CKD is a major area of investigation because it is the ninth most common cause of death in the United States. The incidence of kidney infection can be correlated with kidney malfunction. The main serological markers for renal disease are serum creatinine and creatinine clearance, which are insensitive and nonspecific to recognition of kidney injury. Standard therapy to prevent the progression of CKD includes dietary protein restriction, hypertension control, angiotensin converting enzyme inhibition (ACEi), and angiotensin receptor barricade (ARB). In this review we discuss advances in research on diagnostic biomarkers related to renal diseases and kidney-related injuries.


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