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Critical Reviews™ in Immunology

Publicou 6 edições por ano

ISSN Imprimir: 1040-8401

ISSN On-line: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Dynamics and Function of Solitary Intestinal Lymphoid Tissue

Volume 28, Edição 1, 2008, pp. 1-13
DOI: 10.1615/CritRevImmunol.v28.i1.10
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RESUMO

Peyer's patches are the most prominent organized lymphoid tissue in the intestine and are generally considered to serve as an anatomical platform for the efficient induction of intestinal immune responses. However, besides Peyer's patches, phenotypically diverse, small-sized lymphoid structures are present, which mostly based on their phenotypical differences, have been assigned different names and putative functions. We have recently challenged this view and suggested that these structures represent different manifestations of the very same type of tissue, which we have termed solitary intestinal lymphoid tissue (SILT). A particular hallmark of SILT is its enormous plasticity, reflecting environmental stimuli such as the intestinal microflora. The functional role of SILT has largely been ignored for many years. However, recent reports indicate that SILT serves as port of entry for intestinal antigens and enteropathogens and is involved in the induction of intestinal immune responses. This review focuses on illuminating the concept of SILT and discusses its putative role in mucosal immune responses.

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