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Journal of Environmental Pathology, Toxicology and Oncology

Publicou 4 edições por ano

ISSN Imprimir: 0731-8898

ISSN On-line: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Bioassay-Guided Isolation of Antimutagenic Factors from Fruits of Terminalia Bellerica

Volume 22, Edição 1, 2003, 8 pages
DOI: 10.1615/JEnvPathToxOncol.v22.i1.70
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RESUMO

In the course of our search for novel polyphenolic antimutagenic agents from medicinal plants, we examined water, acetone, and chloroform extracts of Terminalia bellerica for their antimutagenic potency using the Ames Salmonella/microsome assay. Acetone extract exhibited variable inhibitory activity of 65.6%, and 69.7% with 4–O–nitrophenylenediamine (NPD) and sodium azide, respectively (as direct-acting mutagens), and 81.4% with 2–aminofluorene (2AF) (an S9-dependent mutagen), in the preincubation mode of experimentation. Inhibition with chloroform and water extracts was rather insignificant. Studies are well underway to isolate and identify the active polyphenolic compounds from acetone extract, which could be used as effective chemopreventive agents in the future.

CITADO POR
  1. Srinivasa Rao Boddapati, Chandrasekaran C. V., Srikanth H. S., Sasikumar Murugan, Edwin Jothie R., Haseena Begum, Bharathi Bethapudi, Selvam Ramasamy, Prashanth D’Souza, Mutagenicity and Acute Oral Toxicity Test for Herbal Poultry Feed Supplements, Journal of Toxicology, 2018, 2018. Crossref

  2. Sharma Panshul, Verma Kapil Kumar, Raj Hans, Thakur Nutan, A review on ethnobotany, phytochemistry and pharmacology on Terminalia belerica (Bibhitaki), Journal of Drug Delivery and Therapeutics, 11, 1-s, 2021. Crossref

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