Inscrição na biblioteca: Guest
Journal of Environmental Pathology, Toxicology and Oncology

Publicou 4 edições por ano

ISSN Imprimir: 0731-8898

ISSN On-line: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

Indexed in

Photochemoprotective Effect of Calluna vulgaris Extract on Skin Exposed to Multiple Doses of Ultraviolet B in SKH-1 Hairless Mice

Volume 31, Edição 3, 2012, pp. 233-243
DOI: 10.1615/JEnvironPatholToxicolOncol.v31.i3.50
Get accessGet access

RESUMO

UVB is a major cause of nonmelanoma skin cancer in humans. Photochemoprevention represents an important strategy in protecting the skin against the detrimental effects of ultraviolet B (UVB). We investigated the activity of Calluna vulgaris (Cv) delivered via a hydrogel on 3 main pathways (oxidative stress, inflammation, DNA damage) on skin exposed to multiple doses of UVB in SKH-1 mice. Fifty female mice were divided randomly into 5 groups: control, vehicle, UVB irradiated, Cv + UVB irradiated, and Cv + vehicle + UVB irradiated. The extract was applied topically on the skin in a dose of 4 mg polyphenols/cm2 30 minutes before each UVB (240 mJ/cm2) exposure over 10 consecutive days. Malondialdehyde, reduced glutathione, tumor necrosis factor-α, interleukin-6, cyclobutane pyrimidine dimer (CPD) levels, sunburn cell formation and epidermal thickness, and the number of epidermal cell layers in skin were evaluated 24 hours after the last treatment.
UVB increased cytokine levels (P < 0.001), formation of CPDs (P < 0.001) and sunburn cells (P < 0.001), and the epidermal thickness and number of epidermal cell layers (P < 0.001) compared with the control group. The topical application of Cv protected the skin against inflammation and DNA damage, as shown by a decreased number of CPDs (P < 0.001) and sunburn cells (P < 0.001). The administration of Cv via hydrogel may be a viable method for chemoprevention..

CITADO POR
  1. Lorencini Márcio, Brohem Carla A., Dieamant Gustavo C., Zanchin Nilson I.T., Maibach Howard I., Active ingredients against human epidermal aging, Ageing Research Reviews, 15, 2014. Crossref

  2. Brohem Carla Abdo, Di Mambro Valéria Maria, Lorencini Márcio, Therapeutic Alternatives for the Treatment of Epidermal Aging, in Textbook of Aging Skin, 2017. Crossref

  3. Saric Suzana, Sivamani Raja, Polyphenols and Sunburn, International Journal of Molecular Sciences, 17, 9, 2016. Crossref

  4. Azqueta Amaya, Collins Andrew, Polyphenols and DNA Damage: A Mixed Blessing, Nutrients, 8, 12, 2016. Crossref

  5. Brohem Carla Abdo, Di Mambro Valéria Maria, Lorencini Márcio, Therapeutic Alternatives for the Treatment of Epidermal Aging, in Textbook of Aging Skin, 2015. Crossref

  6. Adamtsevich N. Yu., Feskova A. V., Leontiev V. N., Zhavoronok I. P., Yerofeyeva A.-M. V., Mankovskaya S. V., Titok V. V., Wound-healing effect of the gel substance based on the flavonoids complex from extracts of the everlasting(<i>Helichrysum arenarium</i> L.) and the littlewale (<i>Lithospermum officinale</i> L.), Proceedings of the National Academy of Sciences of Belarus, Biological Series, 67, 1, 2022. Crossref

  7. Kahan V., Ribeiro D.A., Egydio F., Barros L.A., Tomimori J., Tufik S., Andersen M.L., Is Lack of Sleep Capable of Inducing DNA Damage in Aged Skin?, Skin Pharmacology and Physiology, 27, 3, 2014. Crossref

  8. Bolfa Pompei, Vidrighinescu Raluca, Petruta Andrei, Dezmirean Dan, Stan Laura, Vlase Laurian, Damian Grigore, Catoi Cornel, Filip Adriana, Clichici Simona, Photoprotective effects of Romanian propolis on skin of mice exposed to UVB irradiation, Food and Chemical Toxicology, 62, 2013. Crossref

  9. Cucu Alexandra-Antonia, Baci Gabriela-Maria, Cucu Alexandru-Bogdan, Dezsi Ştefan, Lujerdean Cristian, Hegeduş Iuliana Cristina, Bobiş Otilia, Moise Adela Ramona, Dezmirean Daniel Severus, Calluna vulgaris as a Valuable Source of Bioactive Compounds: Exploring Its Phytochemical Profile, Biological Activities and Apitherapeutic Potential, Plants, 11, 15, 2022. Crossref

993 Visualizações do artigo 34 downloads de artigos Métricas
993 VISUALIZAÇÕES 34 TRANSFERÊNCIAS 9 Crossref CITAÇÕES Google
Scholar
CITAÇÕES

Artigos com conteúdo semelhante:

Photoprotective Effect of Calluna vulgaris Extract Against UVB-Induced Phototoxicity in Human Immortalized Keratinocytes Journal of Environmental Pathology, Toxicology and Oncology, Vol.30, 2011, issue 4
Olga Soritau, Corina Bianca Tatomir, Gabriela Chereches, Ion Dan Postescu, Maria Perde-Schrepler, Ioana Carmen Brie, Laurian Vlase, Gabriela Adriana Filip, Otilia Barbos, Eva Fischer-Fodor, Piroska Virag
Effects of 10-GHz Microwaves on Hematological Parameters in Swiss Albino Mice and Their Modulation by Prunus avium Journal of Environmental Pathology, Toxicology and Oncology, Vol.32, 2013, issue 3
K. V. Sharma, Rashmi Sisodia, Preeti Srivastava, Faiza Rifat, Archana Sharma
Antioxidant and Radiation Antagonistic Effect of Saraca indica Journal of Environmental Pathology, Toxicology and Oncology, Vol.29, 2010, issue 1
P. Gayathri, P. R. Archana, Bola Sadashiva Satish Rao, Prerana Shetty, Nageshwar Rao
Naringenin Ameliorates Doxorubicin Toxicity and Hypoxic Condition in Dalton's Lymphoma Ascites Tumor Mouse Model: Evidence from Electron Paramagnetic Resonance Imaging Journal of Environmental Pathology, Toxicology and Oncology, Vol.35, 2016, issue 3
Kumaresan Ganesan, Venkatesan Kathiresan, Murugesan Ramachandran, Swathika Subburaman, Mathivanan Natarajan, Arun Venkatesh Krishna, Gandhidasan Rathinasamy
Radioprotection by Copper and Zinc Complexes of 5-Aminosalicylic Acid: A Preliminary Study Journal of Environmental Pathology, Toxicology and Oncology, Vol.27, 2008, issue 2
M. K. Unnikrishnan, S. K. Mantena, K. Chandrasekharan
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa Políticas de preços e assinaturas Begell House Contato Language English 中文 Русский Português German French Spain