Publicou 4 edições por ano
ISSN Imprimir: 0731-8898
ISSN On-line: 2162-6537
Indexed in
DNA Single Strand Breaks Induced by Low Levels of Occupational Exposure to Styrene: The Gap between Standards and Reality
RESUMO
Styrene is a known mutagen and suspected carcinogen, used in the reinforced plastic industry. This study aims to identify the occurrence of DNA single strand breaks (SSBs) in workers exposed to styrene levels far below the recommended standards. We compared 26 exposed workers with 26 control subjects and found a significant increase in the incidence of DNA-SSBs in the exposed individuals. The levels of the biological indices of exposure (urinary mandelic and phenyl glyoxylic acids) were less than 25% of the recommended limits. Reduction of the threshold limit values/time-weighted-average (TLV-TWA) applied is strongly recommended.
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Buschini Annamaria, De Palma Giuseppe, Poli Paola, Martino Anna, Rossi Carlo, Mozzoni Paola, Scotti Eleonora, Buzio Luca, Bergamaschi Enrico, Mutti Antonio, Genetic polymorphism of drug-metabolizing enzymes and styrene-induced DNA damage, Environmental and Molecular Mutagenesis, 41, 4, 2003. Crossref
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Gopinath Ponnusamy Manogaran, Saranya Vinayagam, Vijayakumar Shanmugam, Mythili Meera Mohan, Ruprekha Sharma, Kunal Reshamwala, Pranay Agarwal, Thomas John, Mukherjee Amitava, Chandrasekaran Natarajan, Assessment on interactive prospectives of nanoplastics with plasma proteins and the toxicological impacts of virgin, coronated and environmentally released-nanoplastics, Scientific Reports, 9, 1, 2019. Crossref
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Alimba Chibuisi G., Faggio Caterina, Sivanesan Saravanadevi, Ogunkanmi Adebayo L., Krishnamurthi Kannan, Micro(nano)-plastics in the environment and risk of carcinogenesis: Insight into possible mechanisms, Journal of Hazardous Materials, 416, 2021. Crossref
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Kumar Rakesh, Manna Camelia, Padha Shaveta, Verma Anurag, Sharma Prabhakar, Dhar Anjali, Ghosh Ashok, Bhattacharya Prosun, Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans?, Chemosphere, 298, 2022. Crossref