RT Journal Article ID 5bfffaca2f9e4c2d A1 Abburi , Chandrika A1 Anand, Akshay T1 Ciliary Epithelium: An Underevaluated Target for Therapeutic Regeneration JF Critical Reviews™ in Eukaryotic Gene Expression JO CRE YR 2012 FD 2012-08-02 VO 22 IS 2 SP 87 OP 95 K1 stem cells K1 ciliary epithelium K1 retina K1 vascular niche AB The purpose of stem cells in various organs of vertebrates is to replenish dying cells or to replace damaged tissues. However, a few organs have reasonable, while others have very limited regenerative, capacity. Until the last two decades, the organs such as brain, heart, and kidneys were known to lack regenerative capacity for lack of resident stem cell population. However, with advancement of techniques and an increase in scientific communication, new discoveries have brought novel concepts and data to discover and manipulate these valuable resources. Much focus has been devoted to understanding the regulation and maintenance of these stem cells. We discuss the preclinical data emerging from retino-vascular interactions useful in the exploitation of ciliary epithelium−derived stem cells for therapeutic regeneration. PB Begell House LK https://www.dl.begellhouse.com/journals/6dbf508d3b17c437,7f7fb529655925d5,5bfffaca2f9e4c2d.html