ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
Critical Reviews™ in Physical and Rehabilitation Medicine
SJR: 0.121 SNIP: 0.228 CiteScore™: 0.5

ISSN 印刷: 0896-2960
ISSN オンライン: 2162-6553

Critical Reviews™ in Physical and Rehabilitation Medicine

DOI: 10.1615/CritRevPhysRehabilMed.v13.i1.20
28 pages

Fibromyalgia Syndrome: Toward an Integration of the Literature

Akiko Okifuji
Associate Professor, Department of Anesthesiology, Pain Research and Management Center, University of Utah, UT 84108 University of Washington, Seattle, WA 98195
Michael A. Ashburn
Professor of Anesthesiology and Director of Pain Management Center, University of Utah, UT 84108

要約

Fibromyalgia syndrome (FMS) is a generalized musculoskeletal pain disorder with multiple functional and psychological problems. Despite extensive efforts during the last 30 years to uncover the etiology, the mechanisms underlying FMS remain elusive. Similarly, no single treatment has proven to be universally effective for FMS. FMS is considered to be a medical enigma, and millions of patients continue to suffer from debilitating pain and disability. The primary objective of this article is to present a thorough review of the current FMS literature. We discuss three primary hypotheses on the pathophysiologic mechanisms: peripheral, psychological, and central. We attempt to integrate the findings and suggest a heuristic model of FMS, integrating the physiological and psychological variables with the predispositional, stress, and time factors associated with FMS. This article also includes a review of clinical trials testing various therapy modalities for FMS. The review emphasizes the importance of understanding the multifactorial nature of FMS; different modalities seem to target different areas of the disorder. We suggest that clinical decisions need to reflect the diversity of the FMS symptom profiles. Interdisciplinary treatments tailored to target a patient's specific needs are likely to improve the clinical efficacy and cost-effectiveness of the therapy.


Articles with similar content:

Central Neuropathic Pain in Spinal Cord Injury
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.25, 2013, issue 3-4
Eric Y. Chang, Sujin Lee, Xing Zhao, Sophia Chun, Maya Hatch
Guillain-Barre Syndrome: A Review and Analysis of Current Neurorehabilitation Approaches and Outcomes
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.18, 2006, issue 4
Kevin R. Scott, Daniel M. Chehebar, Milind J. Kothari
Diagnostic Selective Nerve Root Blocks
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.10, 1998, issue 2
Curtis W. Slipman, Randal A. Palmitier
Obstructive Sleep Apnea: Part II. Surgical Approaches to Sleep Apnea
Journal of Long-Term Effects of Medical Implants, Vol.14, 2004, issue 3
Thomas J. Gampper, Martin Hoard, Jeremy A. Benedetti
Carpal Tunnel Syndrome: A Critical Review
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.13, 2001, issue 1
Julie K. Wilson, David E. Kipp