ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
International Journal of Fluid Mechanics Research
ESCI SJR: 0.206 SNIP: 0.446 CiteScore™: 0.5

ISSN 印刷: 2152-5102
ISSN オンライン: 2152-5110

巻:
巻 46, 2019 巻 45, 2018 巻 44, 2017 巻 43, 2016 巻 42, 2015 巻 41, 2014 巻 40, 2013 巻 39, 2012 巻 38, 2011 巻 37, 2010 巻 36, 2009 巻 35, 2008 巻 34, 2007 巻 33, 2006 巻 32, 2005 巻 31, 2004 巻 30, 2003 巻 29, 2002 巻 28, 2001 巻 27, 2000 巻 26, 1999 巻 25, 1998 巻 24, 1997 巻 23, 1996 巻 22, 1995

International Journal of Fluid Mechanics Research

DOI: 10.1615/InterJFluidMechRes.v24.i4-6.130
pages 568-577

Application of Laser Diagnostic Techniques to Characterize the Spray Issued from a pMDI

C. A. Dunbar
Thermo-Fluids Division, Department of Mechanical Engineering, UMIST, Manchester, U.K.
J. F. Miller
Inhalation Product Development, GlaxoWellcome R&D, Hertfordshire, U.K.

要約

The pressurized metered-dose inhaler (pMDI) is a compact pressurized spray dispenser designed for the oral inhalation of multiple doses of finely dispersed drug in the treatment of various pulmonary diseases, the most common being asthma. This research was concerned with the experimental investigation of the spray issued from a pMDI and has been motivated by the urgent need to find suitable replacements to the environmentally destructive CFC-based propellants currently used in the device and to further the understanding of the mechanisms of atomization. The experimental work was conducted using 1-D phase-Doppler particle analyzer (PDPA), yielding the most detailed temporal and spatial analysis of the pMDI spray to date. Two formulations were studied to compare the performance of an 'ozone-friendly' hydrofluoroalkane propellant against that of a traditional placebo CFC-based mixture. The PDPA analysis was complemented by a visual investigation of the near-orifice flow field using copper laserstrobe micro-cinematography in an attempt to obtain information on the primary atomization process of the pMDI. This work was conducted in parallel with the theoretical investigation of the spray issued from a pMDI.


Articles with similar content:

ATOMIZATION OF GELLED PROPELLANTS FROM SWIRL INJECTORS WITH LEAF SPRING IN SWIRL CHAMBER
Atomization and Sprays, Vol.21, 2011, issue 11
Ming-Xi Tong, Wei Zhang, Qing-Fei Fu, Li-Jun Yang, Ming-long Du
PARTICLE LADEN AIR FLOW VISUALIZATION IN A MULTI-ROTOR CONFIGURATION OF A LAWN MOWER HOUSING
Journal of Flow Visualization and Image Processing, Vol.6, 1999, issue 1
F. Saldarriaga, Sandip Dutta, A. Noman
MACROSCOPIC AND MICROSCOPIC CHARACTERISTICS OF GASOLINE AND BUTANOL SPRAY ATOMIZATION UNDER ELEVATED AMBIENT PRESSURES
Atomization and Sprays, Vol.28, 2018, issue 9
Yanfei Li, Hengjie Guo, Yitao Shen, Liuyang Feng, Xiao Ma, Longfei Chen
SPRAY CHARACTERIZATION IN A CONFINED FLOW
ICLASS 94
Proceedings of the Sixth International Conference on Liquid Atomization and Spray Systems, Vol.0, 1994, issue
G. Lavergne, F. Bismes , P. Trichet
CHARACTERISTICS OF SPRAYS THROUGH A WALL IMPINGEMENT INJECTOR
Atomization and Sprays, Vol.14, 2004, issue 4
Takao Inamura, Terutoshi Tomoda