ライブラリ登録: Guest
International Journal of Medicinal Mushrooms

年間 12 号発行

ISSN 印刷: 1521-9437

ISSN オンライン: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Cytotoxic Activities of Fractions of the Willow Bracket Medicinal Mushroom, Phellinus igniarius (Agaricomycetes), and the Induction of Cell Cycle Arrest and Apoptosis in MGC-803 Cells

巻 19, 発行 6, 2017, pp. 561-570
DOI: 10.1615/IntJMedMushrooms.v19.i6.70
Get accessGet access

要約

Phellinus igniarius, a perennial medicinal mushroom, has been used in China and other countries of East Asia for the treatment of various diseases, including cancer. The purpose of this study is to evaluate the cytotoxic activities of different fractions of an ethanol extract from Ph. igniarius and to elucidate a possible antitumor mechanism. An ethanol extract of Ph. igniarius was partitioned into a petroleum ether fraction, an ethyl acetate fraction (EAF), an n-butanol fraction, and a water-soluble fraction. The cytotoxic activity of all the fractions was initially screened in a brine shrimp lethality test, then evaluated by the Cell Counting Kit-8 assay against 5 human tumor cell lines: MGC-803, BEL-7402, HeLa, MCF-7, and HCT-116. The cell cycle distribution induced by EAF on MGC-803 cells was analyzed by flow cytometry with propidium iodide staining, and apoptosis was determined using flow cytometry with Annexin V/propidium iodide staining. The results of the brine shrimp lethality test and the Cell Counting Kit-8 assay showed that EAF was the most active fraction, displaying strong inhibitory activity against the MGC-803, BEL-7402, and MCF-7 cancer cell lines. Flow cytometry analysis indicated that EAF could induce S-phase cell cycle arrest in MGC-803 cells and cause apoptosis in a concentration-dependent manner. This study demonstrated that EAF, as the most active fraction of Ph. igniarius, exerted antitumor activity by inducing MGC-803 cell apoptosis via S-phase cell cycle arrest.

によって引用された
  1. Sun Yuqing, Zhong Shi, Yu Jiaqi, Zhu Jianxun, Ji Dongfeng, Hu Guiyan, Wu Chongming, Li Yougui, Singh Udai P., The aqueous extract of Phellinus igniarius (SH) ameliorates dextran sodium sulfate-induced colitis in C57BL/6 mice, PLOS ONE, 13, 10, 2018. Crossref

  2. Yang Yue, He Pingya, Li Ning, The Antitumor Potential of Extract of the Oak Bracket Medicinal Mushroom Inonotus baumii in SMMC-7721 Tumor Cells, Evidence-Based Complementary and Alternative Medicine, 2019, 2019. Crossref

  3. Sun Yuqing, Zhong Shi, Deng Bo, Jin Qinsheng, Wu Jie, Huo Jinxi, Zhu Jianxun, Zhang Cheng, Li Yougui, Impact of Phellinus gilvus mycelia on growth, immunity and fecal microbiota in weaned piglets, PeerJ, 8, 2020. Crossref

  4. Mehreen Sadaf Huma, Bibi Yamin, Arshad Muhammad, Razzaq Abdul, Ahmad Shakil, Iriti Marcello, Qayyum Abdul, Analysis of Peganum harmala, Melia azedarach and Morus alba extracts against six lethal human cancer cells and oxidative stress along with chemical characterization through advance Fourier Transform and Nuclear Magnetic Resonance spectroscopic methods towards green chemotherapeutic agents, Saudi Pharmaceutical Journal, 29, 6, 2021. Crossref

  5. Nowakowski Patryk, Markiewicz-Żukowska Renata, Bielecka Joanna, Mielcarek Konrad, Grabia Monika, Socha Katarzyna, Treasures from the forest: Evaluation of mushroom extracts as anti-cancer agents, Biomedicine & Pharmacotherapy, 143, 2021. Crossref

1421 記事の閲覧数 25 記事のダウンロード 記事の統計
1421 記事の閲覧数 25 記事のダウンロード 5 Crossref 引用数 Google
Scholar
引用数

類似内容の記事:

Antiproliferative Activity of Some Higher Mushrooms from Hungary against Human Cancer Cell Lines International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 12
Attila Vanyolos, Istvan Zupko, Noemi Bozsity, Judit Hohmann, Bernadett Kovacs
Dichlormethane Extract of the Jelly Ear Mushroom Auricularia auricula-judae (Higher Basidiomycetes) Inhibits Tumor Cell Growth In Vitro International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 1
Md.Ahsanur Reza, Md. Akil Hossain, Seung-Chun Park, Woo-Sik Jo, Seung-Jin Lee, Joo-Won Suh, Sileshi Belew Yohannes, Dereje Damte, Man-hee Rhee
Antitumor Activity of Extracts from Medicinal Basidiomycetes Mushrooms International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 11
Elena Vetchinkina, Galina Maslyakova, Valentina E. Nikitina, Alla Bucharskaya, Nikita Navolokin, Artur Prilepskii, Andrey Burov, Alexandr Shirokov
Cytotoxicity of Medicinal Mushrooms Oudemansiella canarii and Ganoderma lucidum (Agaricomycetes) Against Hematologic Malignant Cells via Activation of Apoptosis-Related Markers International Journal of Medicinal Mushrooms, Vol.24, 2022, issue 11
Sofronio P. Kalaw, Braham Dhillon, Rich Milton R. Dulay, Seemanti Chakrabarti, Renato G. Reyes, Benigno C. Valdez, Esperanza C. Cabrera
Antitumor Effects of Extract of the Oak Bracket Medicinal Mushroom, Phellinus baumii (Agaricomycetes), on Human Melanoma Cells A375 In Vitro and In Vivo International Journal of Medicinal Mushrooms, Vol.22, 2020, issue 2
Qian Chen, Ning Li , Wei-Li Lu, Yue Yang, Lan Zhang
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集 価格及び購読のポリシー Begell House 連絡先 Language English 中文 Русский Português German French Spain