ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
International Journal of Medicinal Mushrooms
インパクトファクター: 1.423 5年インパクトファクター: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN 印刷: 1521-9437
ISSN オンライン: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v4.i2.70
8 pages

Melanin Complex from Medicinal Mushroom Inonotus obliquus (Pers.: Fr.) Pilat (Chaga) (Aphyllophoromycetideae)

Nina A. Bisko
Institute of Food Biotechnology and Genomics of the National Academy of Sciences of Ukraine, Kiev
Nadezda Yu. Mitropolskaya
M. G. Kholodny Institute of Botany, National Academy of Sciences of Ukraine, Tereschenkivska Str. 2, Kiev, 252601, Ukraine
Natalia V. Ikonnikova
Institute of Microbiology of the National Academy of Sciences of Byelorussia, 2 Kuprevich Str., Minsk 220141, Belarus

要約

The production of melanin complex of Inonotus obliquus (Pers.: Fr.) Pilat (Chaga in Russian) in submerged conditions was studied. It was demonstrated that copper ions (0.008%), pyrocatechol (1.0 mM), and tyrosine (20.0 mM) stimulated this process. It has been estimated that melanin of I. obliquus has antioxidant and genoprotective effects. The investigation of the element composition of the pigment shows that it contains 38.2% C, 5.54% H, and trace amounts of N. The pigment was characterized by the following properties: the extinction coefficient E 0.001% (l = 465 nm) = 0.02; content of COOH groups = 0.93%, CO groups = 1.05%, OCH3 groups = 0.96%, total OH groups 16.9% including aliphatic groups 15.65% and phenolic groups 1.25%. The data obtained in our work demonstrate high antioxidant and genoprotective effects of I. obliquus melanin on peroxidasecatalyzed oxidation of aminodiphenyls. These properties of melanin of I. obliquus may be used for the development of anticarcinogenic preparations.


Articles with similar content:

In Vitro Protective Effects of Terminalia arjuna Bark Extracts Against the 4-Nitroquinoline-N-Oxide Genotoxicity
Journal of Environmental Pathology, Toxicology and Oncology, Vol.21, 2002, issue 1
Milena Villarini, Giuseppina Scassellati-Sforzolini, Cristina Fatigoni, Subodh Kumar, Massimiliano Marcarelli, Satwinderjeet Kaur, Massimo Moretti, Iqbal S. Grover, Rossana Pasquini
Suppressive Effect of Natural Sesquiterpenoids on Inducible Cyclooxygenase (COX-2) and Nitric Oxide Synthase (iNOS) Activity in Mouse Macrophage Cells
Journal of Environmental Pathology, Toxicology and Oncology, Vol.21, 2002, issue 2
Won-Yoon Chung, O-Jin Oh, Chai-Hee Hong, Jae-Kwan Hwang, Sun-Sook Kim, Sang Kook Lee, Sun-Kyung Huh, Kwang-Kyun Park, Hye-Young Min
Assessment of Cuproxyl Toxicity by the Method of Bioassay Using Cladocera
Hydrobiological Journal, Vol.37, 2001, issue 6
E. P. Shcherban', I. M. Konovets
Marine microalgae and biological control of phytophagous insects
International Journal on Algae, Vol.3, 2001, issue 1
L. A. Pautova, V. A. Silkin, Ye. B. Gol'din
Antioxidant System of Spirulina platensis (Nordst.) Geitler under the LED Lighting of Different Spectral Compositions
International Journal on Algae, Vol.18, 2016, issue 2
Y. V. Viazau, N. V. Kozel, E. E. Manankina, I. A. Dremuk, K. O. Adamchyk, S. M. Savina