ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
International Journal of Medicinal Mushrooms
インパクトファクター: 1.423 5年インパクトファクター: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN 印刷: 1521-9437
ISSN オンライン: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v4.i2.40
14 pages

Biological Activity of Cordyceps (Fr.) Link Species (Ascomycetes) Derived from a Natural Source and from Fermented Mycelia on Diabetes in STZ-Induced Rats

Tai-Hao Hsu
Department of Medicinal Botanicals and Health Applications, Da-Yeh University, Datsuen, Changhua, 51591, Taiwan (R. O. C.); Department of Bioindustry Technology, Da-Yeh University, Datsuen, Changhua, 51591, Taiwan (R. O. C.)
Hui-Chen Lo
Department of Nutritional Science, Fu Jen Catholic University, New Taipei City, Taiwan

要約

The Chinese traditional herb medicine Cordyceps (natural source) and the mycelial preparations of different species of genus Cordyceps (Fr.) Link (fermented mycelia) produced by fermentation, as well as a commercial product, have been compared in terms of biological activity of in a diabetic animal model using STZ-induced rats. The respective changes of several indices in serum substrate levels and blood analysis, and relative organ weights, were characterized to judge the ability of these preparations of meliorating diabetes by the consecutive intake intragastrically for 14 days. There were significant differences statistically both in the daily average water intake and the daily average urine volume of the STZ-treated group with naturally produced of Cordyceps compared to those of the fermentated mycelial preparations. Although there were no differences in plasma glucose levels among between the Cordyceps-treated group and that of the Cordyceps-untreated STZ rats, all the values of glucose, albumin, cholesterol, HDLcholesterol, triglycerides, BUN in serum, and WBC, RBC, Ht, and MCH in the blood for of the Cordyceps-treated diabetic rats are were between those of the Cordyceps-untreated diabetic rats and the control group. The effects of all the Cordyceps preparations were not reflected in changes of relative organ weight of the rats. This combination of events suggested that a mild and inconspicuous improvement of severe diabetes in STZ-treated rats with the Cordyceps preparations under the experimental conditions. In general, there were no differences between the naturally produced and fermented mycelia of Cordyceps in alleviating diabetes in the present experiments.


Articles with similar content:

Hypotensive Activity of Mushroom Lectin of Tricholoma mongolicum S. Imai (Agaricomycetideae) in Comparison with Some Plant Lectins
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 4
Vincent Eng Choo Ooi, Hexiang Wang, Tzi Bun Ng
Effect of Polysaccharide from Cordyceps militaris (Ascomycetes) on Physical Fatigue Induced by Forced Swimming
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 12
Yan-Feng Xu
The Hepatoprotective Effect of Clidemia hirta against Carbon Tetrachloride (CCl4)−Induced Oxidative Stress and Hepatic Damage in Mice
Journal of Environmental Pathology, Toxicology and Oncology, Vol.36, 2017, issue 4
Mohammad Iqbal, Nurul Amzar
Thirteen-Week Oral Toxicity Evaluation of Erinacine AEnriched Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Sprague-Dawley Rats
International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 4
Wan-Ping Chen, Kwong-Chung Tung, I-Chen Li, Chin-Chu Chen, Li-Ya Lee, Yueh-Ting Tsai
Assessment of the Safety of the Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), in Rats: Biochemical, Hematological, and Antioxidative Parameters
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 10
Daiane Cristovam Rosa Bueno, Marli Gerenutti, Sara Rosicler Vieira Spim, Susi Rosa da Costa, Denise Grotto, Gabriela Karine de Almeida Ramos