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Critical Reviews™ in Eukaryotic Gene Expression
インパクトファクター: 1.841 5年インパクトファクター: 1.927 SJR: 0.649 SNIP: 0.516 CiteScore™: 1.96

ISSN 印刷: 1045-4403
ISSN オンライン: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukaryotGeneExpr.2018020389
pages 25-66

Investigations of Phytochemical Constituents and Their Pharmacological Properties Isolated from the Genus Urtica: Critical Review and Analysis

Muhammad Ibrahim
Department of Applied Chemistry, Government College University Faisalabad, Pakistan
Kanwal Rehman
Institute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad, Pakistan
Aneeza Razzaq
Department of Applied Chemistry, Government College University Faisalabad, Pakistan
Iqbal Hussain
Department of Environmental Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai 980-8579 Japan; Department of Botany, Government College University, Faisalabad, Pakistan
Tahir Farooq
Department of Applied Chemistry, Government College University, Faisalabad, Pakistan
Amjad Hussain
Department of Applied Chemistry, Government College University Faisalabad, Pakistan
Muhammad Sajid Hamid Akash
Government College University Faisalabad, Pakistan

要約

The genus Urtica belongs to the family Urticaceae. The plants of this genus are known as nettles or, quite often, as stinging nettles. These plants can be easily identified by the presence of stinging hairs. Urtica species have previously been used for various medicinal purposes. The history for the use of these plants for medicinal purposes starts from the Bronze Age (3000–2000 BC). Medicinally, the genus Urtica has been used to treat several disorders, such as cancer, rheumatoid arthritis, bronchitis, diarrhea, sprains, kidney stones, urinary tract infection, high blood pressure, hemorrhoids, flu, cough, fever, and ulcers. Scientific reports on the phytochemical analysis of this genus has so far revealed more than 123 compounds from this genus, including terpenoids, flavonoids, lignans, sterols, and polyphenols, have been isolated. Various biological activities have been exhibited by these compounds, such as antihypertensive, hepatoprotective, nephroprotective, antiurolithiatic, anthelmintic, diuretic, antinoceceptive, antidiabetic, antiviral, , and immunomodulatory. In this article, we mainly emphasize the phytochemical composition, therapeutic applications, and ethnopharmacological values of various species of genus Urtica.


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