年間 6 号発行
ISSN 印刷: 1045-4403
ISSN オンライン: 2162-6502
Indexed in
Expression of Gstt1 in Type 2 Diabetic Retinopathy Patients
要約
Type 2 diabetes mellitus (T2DM) is the most common metabolic and multifactorial disease in which both genetic and environmental factors are involved. In diabetes, the defects in the cellular metabolism result in higher levels of free radicals. These radicals react with other vital cellular molecules, which are responsible in diabetes side effects and known as diabetic retinopathy (DR), a disease of the retina that results in impairment or loss of vision. In the present study, we investigated the expression of glutathione S-transferases class theta 1 (GSTT1) in type 2 DR subjects. Highly significant differences (P ≤ 0.05) were observed in GSST1 expression in DR patients compared with diabetic and control groups.
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Hashemi-Soteh Mohammad Bagher, Ahmadzadeh Amiri Amir, Sheikh Rezaee Majid Reza, Ahmadzadeh Amiri Ali, Ahrari Rohodin, Ahmadzadeh Amiri Ahmad, Daneshvar Fatemeh, Evaluation of glutathione S-transferase polymorphism in Iranian patients with type 2 diabetic microangiopathy, Egyptian Journal of Medical Human Genetics, 21, 1, 2020. Crossref