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Critical Reviews™ in Eukaryotic Gene Expression

年間 6 号発行

ISSN 印刷: 1045-4403

ISSN オンライン: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Heparan Sulfate-based Treatments for Regenerative Medicine

巻 21, 発行 1, 2011, pp. 1-12
DOI: 10.1615/CritRevEukarGeneExpr.v21.i1.10
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要約

This review summarizes the emerging strategies that exploit the glycosaminoglycan sugar, heparan sulfate (HS), either as a substitute for, or as a supplement to growth factor (GF) therapy for regenerative medicine. Excluding autograft, the administration of GFs is currently the most effective treatment for critical bone repair and restoration. However, major hurdles in the clinical development of GF therapies include the high cost, the unwanted side effects, and the toxicity associated with the physiological overdosing required to achieve a successful outcome. These drawbacks may be overcome with the application of particular HS fractions that have been optimized to bind, recruit and enhance the biological activity of endogenous GF at the site of injury. Three HS-based treatments are discussed here: first, the single, localized, and sustained delivery of HS as a stand-alone therapeutic agent; then, the inclusion of an HS component within a delivery device so as to stabilize and potentiate the bioactivity of the incorporated GF; and finally, the growing use of HS mimetics, particularly for bone repair.

によって引用された
  1. Büttner Marianne, Möller Stephanie, Keller Mario, Huster Daniel, Schiller Jürgen, Schnabelrauch Matthias, Dieter Peter, Hempel Ute, Over-sulfated chondroitin sulfate Derivatives induce osteogenic differentiation of hMSC independent of BMP-2 and TGF-β1 signalling, Journal of Cellular Physiology, 228, 2, 2013. Crossref

  2. Lorden Elizabeth R., Levinson Howard M., Leong Kam W., Integration of drug, protein, and gene delivery systems with regenerative medicine, Drug Delivery and Translational Research, 5, 2, 2015. Crossref

  3. Xu Ruoyan, Rudd Timothy R., Hughes Ashley J, Siligardi Giuliano, Fernig David G., Yates Edwin A., Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network, FEBS Journal, 280, 10, 2013. Crossref

  4. Murali S., Rai B., Dombrowski C., Lee J.L.J., Lim Z.X.H., Bramono D.S., Ling L., Bell T., Hinkley S., Nathan S.S., Hui J.H., Wong H.K., Nurcombe V., Cool S.M., Affinity-selected heparan sulfate for bone repair, Biomaterials, 34, 22, 2013. Crossref

  5. Princz M.A., Sheardown H., Heparin-modified dendrimer crosslinked collagen matrices for the delivery of heparin-binding epidermal growth factor, Journal of Biomedical Materials Research Part A, 100A, 8, 2012. Crossref

  6. He Hongyan, Liu Changsheng, Stem Cell Differentiation Mediated by Biomaterials/Surfaces, in Polymeric Biomaterials for Tissue Regeneration, 2016. Crossref

  7. Melrose James, Glycosaminoglycans in Wound Healing, Bone and Tissue Regeneration Insights, 7, 2016. Crossref

  8. Jiang Xianfang, Liu Junting, Liu Qin, Lu Zhenhui, Zheng Li, Zhao Jinmin, Zhang Xingdong, Therapy for cartilage defects: functional ectopic cartilage constructed by cartilage-simulating collagen, chondroitin sulfate and hyaluronic acid (CCH) hybrid hydrogel with allogeneic chondrocytes, Biomaterials Science, 6, 6, 2018. Crossref

  9. Liu Yi, Xu Zhujie, Wang Qiqi, Jiang Yuyu, Wang Rui, Chen Shayang, Zhu Jingyu, Zhang Yan, Chen Jinghua, Selective regulation of RANKL/RANK/OPG pathway by heparan sulfate through the binding with estrogen receptor β in MC3T3-E1 cells, International Journal of Biological Macromolecules, 161, 2020. Crossref

  10. Zhao Yunlong, Abzalimov Rinat R., Kaltashov Igor A., Interactions of Intact Unfractionated Heparin with Its Client Proteins Can Be Probed Directly Using Native Electrospray Ionization Mass Spectrometry, Analytical Chemistry, 88, 3, 2016. Crossref

  11. Filipczak Nina, Yalamarty Satya Siva Kishan, Li Xiang, Khan Muhammad Muzamil, Parveen Farzana, Torchilin Vladimir, Lipid-Based Drug Delivery Systems in Regenerative Medicine, Materials, 14, 18, 2021. Crossref

  12. Rinker Torri E., Philbrick Brandon D., Hettiaratchi Marian H., Smalley David M., McDevitt Todd C., Temenoff Johnna S., Microparticle-mediated sequestration of cell-secreted proteins to modulate chondrocytic differentiation, Acta Biomaterialia, 68, 2018. Crossref

  13. Hintze Vera, Samsonov Sergey A., Anselmi Massimiliano, Moeller Stephanie, Becher Jana, Schnabelrauch Matthias, Scharnweber Dieter, Pisabarro M. Teresa, Sulfated Glycosaminoglycans Exploit the Conformational Plasticity of Bone Morphogenetic Protein-2 (BMP-2) and Alter the Interaction Profile with Its Receptor, Biomacromolecules, 15, 8, 2014. Crossref

  14. Rother Sandra, Salbach-Hirsch Juliane, Moeller Stephanie, Seemann Thomas, Schnabelrauch Matthias, Hofbauer Lorenz C., Hintze Vera, Scharnweber Dieter, Bioinspired Collagen/Glycosaminoglycan-Based Cellular Microenvironments for Tuning Osteoclastogenesis, ACS Applied Materials & Interfaces, 7, 42, 2015. Crossref

  15. Li Qiu, Niu Yiming, Diao Huajia, Wang Lintao, Chen Xiuping, Wang Yitao, Dong Lei, Wang Chunming, In situ sequestration of endogenous PDGF-BB with an ECM-mimetic sponge for accelerated wound healing, Biomaterials, 148, 2017. Crossref

  16. Zhao Shancheng, Wang Zhen, Chen Jingxiao, Chen Jinghua, Preparation of heparan sulfate-like polysaccharide and application in stem cell chondrogenic differentiation, Carbohydrate Research, 401, 2015. Crossref

  17. Xu Zhujie, Chen Shayang, Feng Dehong, Liu Yi, Wang Qiqi, Gao Tianshu, Liu Zhenwei, Zhang Yan, Chen Jinghua, Qiu Lipeng, Biological role of heparan sulfate in osteogenesis: A review, Carbohydrate Polymers, 272, 2021. Crossref

  18. Rai B., Chatterjea A., Lim Z.X.H., Tan T.C., Sawyer A.A., Hosaka Y.Z., Murali S., Lee J.J.L., Fenwick S.A., Hui J.H., Nurcombe V., Cool S.M., Repair of segmental ulna defects using a β-TCP implant in combination with a heparan sulfate glycosaminoglycan variant, Acta Biomaterialia, 28, 2015. Crossref

  19. Rnjak‐Kovacina Jelena, Tang Fengying, Whitelock John M., Lord Megan S., Glycosaminoglycan and Proteoglycan‐Based Biomaterials: Current Trends and Future Perspectives, Advanced Healthcare Materials, 7, 6, 2018. Crossref

  20. Smith Margaret M., Hayes Anthony J., Melrose James, Pentosan Polysulfate, a Semisynthetic Heparinoid Disease-Modifying Osteoarthritic Drug with Roles in Intervertebral Disc Repair Biology Emulating the Stem Cell Instructive and Tissue Reparative Properties of Heparan Sulfate, Stem Cells and Development, 31, 15-16, 2022. Crossref

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