ライブラリ登録: Guest
Atomization and Sprays

年間 12 号発行

ISSN 印刷: 1044-5110

ISSN オンライン: 1936-2684

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00095 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.28 SJR: 0.341 SNIP: 0.536 CiteScore™:: 1.9 H-Index: 57

Indexed in

THEORETICAL INVESTIGATION OF THE SPRAY FROM A PRESSURIZED METERED-DOSE INHALER

巻 7, 発行 4, 1997, pp. 417-436
DOI: 10.1615/AtomizSpr.v7.i4.60
Get accessGet access

要約

This research was concerned with the theoretical investigation of the spray issued from a pressurized metered-dose inhaler (pMDI). The theoretical investigation of the pMDI spray consisted of constructing a model of the fluid flow through the pMDI that was based on a quasi-steady-state separated flow analysis during a single actuation and included a qualitative and quantitative description of the primary atomization process, the resultant spray model being calculated from the solution of the multiphase transport equations using the discrete droplet model (DDM). The predicted results were validated against detailed temporal and spatial experimental data obtained using phase Doppler particle analysis (PDPA).

によって引用された
  1. Zhu Bing, Traini Daniela, Young Paul, Aerosol particle generation from solution-based pressurized metered dose inhalers: a technical overview of parameters that influence respiratory deposition, Pharmaceutical Development and Technology, 20, 8, 2015. Crossref

  2. Kleinstreuer Clement, Shi Huawei, Zhang Zhe, Computational Analyses of a Pressurized Metered Dose Inhaler and a New Drug–Aerosol Targeting Methodology, Journal of Aerosol Medicine, 20, 3, 2007. Crossref

  3. Bell John, Newman Steve, The rejuvenated pressurised metered dose inhaler, Expert Opinion on Drug Delivery, 4, 3, 2007. Crossref

  4. Smyth Hugh D. C., Multimodal particle size distributions emitted from HFA-134a solution pressurized metered-dose inhalers, AAPS PharmSciTech, 4, 3, 2003. Crossref

  5. Versteeg H K, Hargrave G K, Kirby M, Internal Flow and Near-Orifice Spray Visualisations of a Model Pharmaceutical Pressurised Metered Dose Inhaler, Journal of Physics: Conference Series, 45, 2006. Crossref

  6. Crosland Brian Michael, Johnson Matthew Ronald, Matida Edgar Akio, Characterization of the Spray Velocities from a Pressurized Metered-Dose Inhaler, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 22, 2, 2009. Crossref

  7. DUNBAR C.A., WATKINS A.P., MILLER J.F., An Experimental Investigation of the Spray Issued from a pMDI Using Laser Diagnostic Techniques, Journal of Aerosol Medicine, 10, 4, 1997. Crossref

  8. Ivey James W, Vehring Reinhard, Finlay Warren H, Understanding pressurized metered dose inhaler performance, Expert Opinion on Drug Delivery, 12, 6, 2015. Crossref

  9. Smyth Hugh DC, Propellant-driven metered-dose inhalers for pulmonary drug delivery, Expert Opinion on Drug Delivery, 2, 1, 2005. Crossref

  10. Smyth Hugh D. C., Beck Vance P., Williams Dennis, Hickey Anthony J., The influence of formulation and spacer device on the in vitro performance of solution chlorofluorocarbon-free propellant-driven metered dose inhalers, AAPS PharmSciTech, 5, 1, 2004. Crossref

  11. Smyth Hugh, Brace Geoff, Barbour Tony, Gallion Jim, Grove Joe, Hickey Anthony J., Spray Pattern Analysis for Metered Dose Inhalers: Effect of Actuator Design, Pharmaceutical Research, 23, 7, 2006. Crossref

  12. Hickey Anthony J., Holt Jay, Surface interactions in propellant driven metered dose inhaler product design, in Colloid and Interface Science in Pharmaceutical Research and Development, 2014. Crossref

  13. Ruzycki Conor A, Javaheri Emadeddin, Finlay Warren H, The use of computational fluid dynamics in inhaler design, Expert Opinion on Drug Delivery, 10, 3, 2013. Crossref

  14. Martin Andrew R., Finlay Warren H., Aerosol Drug Delivery to the Lungs, in Pharmaceutical Sciences Encyclopedia, 2011. Crossref

  15. Zhu Bing, Traini Daniela, Chan Hak-Kim, Young Paul M., The effect of ethanol on the formation and physico-chemical properties of particles generated from budesonide solution-based pressurized metered-dose inhalers, Drug Development and Industrial Pharmacy, 39, 11, 2013. Crossref

  16. Stein Stephen W., Myrdal Paul B., The Relative Influence of Atomization and Evaporation on Metered Dose Inhaler Drug Delivery Efficiency, Aerosol Science and Technology, 40, 5, 2006. Crossref

  17. Smyth Hugh D.C, The influence of formulation variables on the performance of alternative propellant-driven metered dose inhalers, Advanced Drug Delivery Reviews, 55, 7, 2003. Crossref

  18. Smyth Hugh D. C., Beck Vance P., Williams Dennis, Hickey Anthony J., The influence of formulation and spacer device on the in vitro performance of solution chlorofluorocarbon-free propellant-driven metered dose inhalers, AAPS PharmSciTech, 5, 1, 2004. Crossref

  19. Jones Latarsha, Garcia-Contreras Lucila, Smyth Hugh, Garmise Robert, Hickey Anthony, Cooney Daniel, Medical and pharmaceutical aerosols, in Aerosols Handbook, 2004. Crossref

  20. Stein Stephen W., Sheth Poonam, Hodson P. David, Myrdal Paul B., Advances in Metered Dose Inhaler Technology: Hardware Development, AAPS PharmSciTech, 15, 2, 2014. Crossref

  21. Marek Stephen, Smyth Hugh, Garcia-Contreras Lucila, Cooney Daniel, Garmise Robert, Jones Latarsha, Hickey Anthony, Medical and Pharmaceutical Aerosols, in Aerosols Handbook, 2012. Crossref

  22. Murnane Darragh, Hutter Victoria, Harang Marie, Pharmaceutical Aerosols and Pulmonary Drug Delivery, in Aerosol Science, 2014. Crossref

  23. Ivey James W., Lewis David, Church Tanya, Finlay Warren H., Vehring Reinhard, A correlation equation for the mass median aerodynamic diameter of the aerosol emitted by solution metered dose inhalers, International Journal of Pharmaceutics, 465, 1-2, 2014. Crossref

  24. Lee Eunju, Park Jinwoo, Huh Kang Y., Choi Jaejoon, Bae Choongsik, Simulation of Fuel/Air Mixture Formation for Heavy Duty Liquid Phase LPG Injection (LPLI) Engines, SAE Technical Paper Series, 1, 2003. Crossref

  25. Finlay Warren H., Metered dose propellant inhalers, in The Mechanics of Inhaled Pharmaceutical Aerosols, 2001. Crossref

  26. Finlay Warren H., Particle size changes due to evaporation or condensation, in The Mechanics of Inhaled Pharmaceutical Aerosols, 2001. Crossref

  27. Watkins A.P., Modelling the mean temperatures used for calculating heat and mass transfer in sprays, International Journal of Heat and Fluid Flow, 28, 3, 2007. Crossref

  28. Aamir M.A., Watkins A.P., Numerical analysis of depressurisation of highly pressurised liquid propane, International Journal of Heat and Fluid Flow, 21, 4, 2000. Crossref

  29. Gavtash B., Versteeg H. K., Hargrave G., Myatt B., Lewis D., Church T., Brambilla G., Transient flashing propellant flow models to predict internal flow characteristics, spray velocity, and aerosol droplet size of a pMDI, Aerosol Science and Technology, 51, 5, 2017. Crossref

  30. Yousefi Morteza, Inthavong Kiao, Tu Jiyuan, Effect of Pressurized Metered Dose Inhaler Spray Characteristics and Particle Size Distribution on Drug Delivery Efficiency, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 30, 5, 2017. Crossref

  31. Gavtash B., Versteeg H. K., Hargrave G., Myatt B., Lewis D., Church T., Brambilla G., Transient aerodynamic atomization model to predict aerosol droplet size of pressurized metered dose inhalers (pMDI), Aerosol Science and Technology, 51, 8, 2017. Crossref

  32. Martin Andrew R., Kwok Daniel Y., Finlay Warren H., Investigating the Evaporation of Metered-Dose Inhaler Formulations in Humid Air: Single Droplet Experiments, Journal of Aerosol Medicine, 18, 2, 2005. Crossref

  33. Longest P. Worth, Hindle Michael, Quantitative Analysis and Design of a Spray Aerosol Inhaler. Part 1: Effects of Dilution Air Inlets and Flow Paths, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 22, 3, 2009. Crossref

  34. Byron Peter R., Hindle Michael, Lange Carlos F., Longest P. Worth, McRobbie Donald, Oldham Michael J., Olsson Bo, Thiel Charles G., Wachtel Herbert, Finlay Warren H., In Vivo–In VitroCorrelations: Predicting Pulmonary Drug Deposition from Pharmaceutical Aerosols, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 23, S2, 2010. Crossref

  35. DUNBAR C.A., ATOMIZAT10N MECHANISMS OF THE PRESSURIZED METERED DOSE INHALER, Particulate Science and Technology, 15, 3-4, 1997. Crossref

  36. Mason-Smith Nicholas, Duke Daniel J., Kastengren Alan L., Traini Daniela, Young Paul M., Chen Yang, Lewis David A., Edgington-Mitchell Daniel, Honnery Damon, Revealing pMDI Spray Initial Conditions: Flashing, Atomisation and the Effect of Ethanol, Pharmaceutical Research, 34, 4, 2017. Crossref

  37. McKiernan Alan Patrick, Inhaler Spray Investigation Using High-Speed Phase-Contrast X-Ray and Schlieren Imaging, Pharmaceutical Research, 36, 8, 2019. Crossref

  38. Finlay Warren H., Metered-dose propellant inhalers, in The Mechanics of Inhaled Pharmaceutical Aerosols, 2019. Crossref

  39. Finlay W. H., Pharmaceutical Aerosol Sprays for Drug Delivery to the Lungs, in Handbook of Atomization and Sprays, 2011. Crossref

  40. Finlay Warren H., Particle size changes due to evaporation or condensation, in The Mechanics of Inhaled Pharmaceutical Aerosols, 2019. Crossref

  41. Xu Zhen, Hickey Anthony J., The Physics of Aerosol Droplet and Particle Generation from Inhalers, in Controlled Pulmonary Drug Delivery, 2011. Crossref

  42. Calay R.K., Holdo A.E., Modelling the dispersion of flashing jets using CFD, Journal of Hazardous Materials, 154, 1-3, 2008. Crossref

Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集 価格及び購読のポリシー Begell House 連絡先 Language English 中文 Русский Português German French Spain