年間 6 号発行
ISSN 印刷: 0743-4863
ISSN オンライン: 2162-660X
Indexed in
Targeted Delivery of Peptides, Proteins, and Genes by Receptor-Mediated Endocytosis
要約
Receptor-mediated endocytosis (RME) is one type of delivery system by which therapeutic agents can be specifically transported to their target. Although many successful studies have been performed at a preclinical level, its clinical application is restricted by a number of factors, including the low targeting efficiency that stems from the characteristics of RME. One important approach to overcome this is to improve the drug delivery system by a series of chemical modifications and evaluate the drug targeting efficiency from a kinetic point of view.
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