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Critical Reviews™ in Therapeutic Drug Carrier Systems

年間 6 号発行

ISSN 印刷: 0743-4863

ISSN オンライン: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

Indexed in

Recent Trends in Microbially and/or Enzymatically Driven Colon-Specific Drug Delivery Systems

巻 28, 発行 6, 2011, pp. 489-552
DOI: 10.1615/CritRevTherDrugCarrierSyst.v28.i6.10
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要約

Colon-specific drug delivery systems have recently gained enormous importance for the delivery of a variety of therapeutic compounds. To deliver a drug molecule intact to the colon, the delivery system must pass through the upper part of the gastrointestinal tract without being degraded. Researchers have attempted various approaches in the formulation of colon-specific drug delivery systems. Among them, the most promising are the microbially and/or enzymatically driven drug delivery systems, consisting of biodegradable polymers (polysaccharides) and prodrugs. The major advantage of the microbially and/or enzymatically driven colon-specific drug delivery systems is that they can sense the arrival of the formulation in the colon and release the drug upon activation. This review familiarizes readers with the recent advancements in microbially and/or enzymatically driven colon-specific drug delivery systems, along with their in vitro and in vivo evaluation.

によって引用された
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