ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
Critical Reviews™ in Immunology
インパクトファクター: 1.404 5年インパクトファクター: 3.347 SJR: 0.706 SNIP: 0.55 CiteScore™: 2.19

ISSN 印刷: 1040-8401
ISSN オンライン: 2162-6472

巻:
巻 40, 2020 巻 39, 2019 巻 38, 2018 巻 37, 2017 巻 36, 2016 巻 35, 2015 巻 34, 2014 巻 33, 2013 巻 32, 2012 巻 31, 2011 巻 30, 2010 巻 29, 2009 巻 28, 2008 巻 27, 2007 巻 26, 2006 巻 25, 2005 巻 24, 2004 巻 23, 2003 巻 22, 2002 巻 21, 2001 巻 20, 2000 巻 19, 1999 巻 18, 1998 巻 17, 1997 巻 16, 1996 巻 15, 1995 巻 14, 1994

Critical Reviews™ in Immunology

DOI: 10.1615/CritRevImmunol.2014010373
pages 121-146

CD4 T-Cell Memory Generation and Maintenance

David J. Gasper
Department of Pathobiological Sciences; Comparative Biomedical Sciences Graduate Program, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA
Melba Marie Tejera
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA
M Suresh
Department of Pathobiological Sciences; Comparative Biomedical Sciences Graduate Program, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA

要約

Immunologic memory is the adaptive immune system's powerful ability to remember a previous antigen encounter and react with accelerated vigor upon antigen re-exposure. It provides durable protection against reinfection with pathogens and is the foundation for vaccine-induced immunity. Unlike the relatively restricted immunologic purview of memory B cells and CD8 T cells, the field of CD4 T-cell memory must account for multiple distinct lineages with diverse effector functions, the issue of lineage commitment and plasticity, and the variable distribution of memory cells within each lineage. Here, we discuss the evidence for lineage-specific CD4 T-cell memory and summarize the known factors contributing to memory-cell generation, plasticity, and long-term maintenance.

キーワード: CD4 T cell, memory, model, Th1, Th2, Tfh, Treg

Articles with similar content:

Crosstalk between T Lymphocytes and Dendritic Cells
Critical Reviews™ in Immunology, Vol.32, 2012, issue 2
Marie Tourret, Claire Hivroz, Karine Chemin, Armelle Bohineust
B Cell–Specific Biomarkers for Optimal Antibody Responses to Influenza Vaccination and Molecular Pathways That Reduce B Cell Function with Aging
Critical Reviews™ in Immunology, Vol.36, 2016, issue 6
Daniela Frasca, Bonnie B. Blomberg
Positive and Negative Thymocyte Selection
Critical Reviews™ in Immunology, Vol.18, 1998, issue 4
Takashi Saito , Norihiko Watanabe
Proteases and Cell-Mediated Cytotoxicity
Critical Reviews™ in Immunology, Vol.18, 1998, issue 3
R. Chris Bleackley, Alison J. Darmon
Important Biology Events and Pathways in Brucella Infection and Implications for Novel Antibiotic Drug Targets
Critical Reviews™ in Eukaryotic Gene Expression, Vol.23, 2013, issue 1
Guangjun Gao, Jie Xu