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Journal of Long-Term Effects of Medical Implants

年間 4 号発行

ISSN 印刷: 1050-6934

ISSN オンライン: 1940-4379

SJR: 0.184 SNIP: 0.485 CiteScore™:: 1.1 H-Index: 39

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Effects of Hydroxyapatite on Titanium Foam as a Bone Ingrowth Surface in Acetabular Shells: A Canine Study

巻 20, 発行 1, 2010, pp. 35-42
DOI: 10.1615/JLongTermEffMedImplants.v20.i1.50
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要約

This study investigated a highly porous titanium foam with and without a PeriApetite coating as an alternative surface for implant fixation. Twelve mongrel canines received staged total hip replacements under International Animal Care and Use Committee (IACUC) approval from our institution. Animals were randomly placed in three- or six-month groups for sacrifice. Seventeen total hips were available for evaluation. The area and depth of ingrowth was measured by SEM. At three months, PeriApetite Ti foam had 37% more depth and almost 10% more bone ingrowth. Both groups were found not to be different at the six-month mark with over 36% of ingrowth calculated on SEM. The results prove not only that titanium foam is a viable ingrowth surface but also that PA coating can enhance the time to bony incorporation.

によって引用された
  1. Edreira E.R.U., Alghamdi H., Wolke J.G.C., van den Beucken J.J.J.P., Jansen J.A., Material and Biological Issues Related to the Use of Inorganic Materials at the Bone–Implant Interface, in Comprehensive Inorganic Chemistry II, 2013. Crossref

  2. Rentsch Claudia, Schneiders Wolfgang, Manthey Suzanne, Rentsch Barbe, Rammelt Stephan, Comprehensive histological evaluation of bone implants, Biomatter, 4, 1, 2014. Crossref

  3. Berner A., Boerckel J. D., Saifzadeh S., Steck R., Ren J., Vaquette C., Zhang J. Qiyi, Nerlich M., Guldberg R. E., Hutmacher D. W., Woodruff M. A., Biomimetic tubular nanofiber mesh and platelet rich plasma-mediated delivery of BMP-7 for large bone defect regeneration, Cell and Tissue Research, 347, 3, 2012. Crossref

  4. Rentsch Claudia, Schneiders Wolfgang, Hess Ricarda, Rentsch Barbe, Bernhardt Ricardo, Spekl Kathrin, Schneider Konrad, Scharnweber Dieter, Biewener Achim, Rammelt Stefan, Healing properties of surface-coated polycaprolactone-co-lactide scaffolds: A pilot study in sheep, Journal of Biomaterials Applications, 28, 5, 2014. Crossref

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